60010-03-9

Basic information

• Product Name: 2,6-Dichloro-4-methyl-3-nitropyridine
• Synonyms: D90123;2,6-Dichloro-4-Methyl-3-n...;Pyridine, 2,6-dichloro-4-Methyl-3-nitro-;2,6-Dichloro-4-methyl-3-nitropyridine
• CAS NO: 60010-03-9
• Molecular Formula: C₆H₄Cl₂N₂O₂
• Molecular Weight: 207.01
• Product Categories: Heterocycle-Pyridine series;API intermediates
• Mol File: 60010-03-9.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 317 °C
• Flash Point: 145 °C
• Appearance: /
• Density: 1.537
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.591
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -4.96±0.10(Predicted)
• CAS DataBase Reference: 2,6-Dichloro-4-methyl-3-nitropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Dichloro-4-methyl-3-nitropyridine(60010-03-9)
• EPA Substance Registry System: 2,6-Dichloro-4-methyl-3-nitropyridine(60010-03-9)

Safety Data

• Hazardous Substances Data: 60010-03-9(Hazardous Substances Data)

Usage

Uses

2,6-Dichloro-4-methyl-3-nitropyridine is used in preparation of imidazolopyridine derivatives as agricultural fungicides and insecticides.

InChI:InChI=1/C6H4Cl2N2O2/c1-3-2-4(7)9-6(8)5(3)10(11)12/h2H,1H3

Upstream product

• 1253378-56-1 2-chloro-4-methyl-5-nitropyridine-1-oxide 
• 23056-33-9 2-chloro-4-methyl-5-nitro-pyridine 
• 39621-00-6 2,6-dichloro-4-picoline 

Relevant articles and documents

6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS

The present disclosure provides 6-heteroaryloxy benzimidazole and azabenzimidazole compounds and compositions thereof useful for inhibiting JAK2.

FUSED IMIDAZOLE COMPOUNDS

The present invention provides compounds represented by formula (I), pharmaceutically acceptable salts thereof, N-oxides thereof, solvates thereof or prodrugs thereof (wherein the characters are as defined in the description). The compounds represented by formula (I) have affinity and selectivity for the gamma-aminobutyric acid A receptor subunit alpha 5 (GABAA α5) and act as GABAA α5 negative allosteric modulators (GABAA α5 NAM), so that they are useful in the prevention and/or treatment of diseases which are related to the GABAA α5 such as Alzheimer's disease.

PYRROLOPYRROLONE DERIVATIVES AND THEIR USE AS BET INHIBITORS

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.