60011-49-6

Basic information

• Product Name: N-benzyl-N-(2-propynyl)-4-chloroaniline
• Synonyms: N-benzyl-N-(2-propynyl)-4-chloroaniline
• CAS NO: 60011-49-6
• Molecular Weight: 255.747
• Mol File: 60011-49-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-benzyl-N-(2-propynyl)-4-chloroaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-N-(2-propynyl)-4-chloroaniline(60011-49-6)
• EPA Substance Registry System: N-benzyl-N-(2-propynyl)-4-chloroaniline(60011-49-6)

Safety Data

• Hazardous Substances Data: 60011-49-6(Hazardous Substances Data)

Upstream product

• 2948-37-0 N-(4-chlorophenyl)benzylamine 
• 106-96-7 propargyl bromide 
• 106-47-8 4-chloro-aniline 

Relevant articles and documents

Synthesis of 2-Indolyltetrahydroquinolines by Zinc(II)-Catalyzed Intramolecular Hydroarylation-Redox Cross-Dehydrogenative Coupling of N-Propargylanilines with Indoles

An intramolecular hydroarylation-redox cross-dehydrogenative coupling (CDC) of propargylic anilines with indoles proceeded in the presence of zinc(II) catalysts to give 2-indolyltetrahydroquinolines in good to high yields. Three C-H bonds (two sp2and one sp3) are activated in one shot and these hydrogen atoms are trapped by a propargylic triple bond in the molecule.

Zinc(ii)-catalyzed intramolecular hydroarylation-redox cross-dehydrogenative coupling of N -propargylanilines with diverse carbon pronucleophiles: Facile access to functionalized tetrahydroquinolines

Zinc(ii)-catalyzed intramolecular hydroarylation-redox cross-dehydrogenative coupling of N-propargylanilines with two types of carbon pronucleophiles (nitromethane as a sp3 carbon pronucleophile and phenylacetylenes as sp carbon pronucleophiles) proceeded to give the 2-substituted tetrahydroquinolines in good yields with 100percent atomic utilization without any additional external oxidants.