60012-49-9

Usage

Uses

Used in Pharmaceutical and Organic Chemical Synthesis:
2-(2-CHLOROETHYL)PIPERIDINUM CHLORIDE is used as an intermediate for the synthesis of various pharmaceuticals and organic chemicals. Its unique structure and reactivity make it a valuable component in the development of new compounds with potential therapeutic or functional uses.
Used in the Preparation of Quaternary Ammonium Compounds:
In the chemical industry, 2-(2-CHLOROETHYL)PIPERIDINUM CHLORIDE is utilized as a reactant in the preparation of quaternary ammonium compounds. These compounds have a wide range of applications, including as surfactants, phase-transfer catalysts, and antimicrobial agents.
Used in the Preparation of Ionic Liquids:
2-(2-CHLOROETHYL)PIPERIDINUM CHLORIDE is also used in the synthesis of ionic liquids, which are salts with melting points below 100°C. These liquids have gained significant interest due to their potential use as solvents, electrolytes, and in various other applications that can benefit from their unique properties.
Used in Organic Synthesis:
2-(2-CHLOROETHYL)PIPERIDINUM CHLORIDE serves as a building block in organic synthesis, where it can be used to construct more complex molecules with specific functions or properties.
Used in Drug Development:
2-(2-CHLOROETHYL)PIPERIDINUM CHLORIDE has potential applications in drug development, where it may contribute to the creation of new pharmaceutical agents through its reactivity and structural features.
Used in Materials Science:
Its potential applications in materials science include the development of new materials with unique properties, such as improved conductivity, stability, or responsiveness to stimuli.

InChI:InChI=1/C7H14ClN.ClH/c8-5-4-7-3-1-2-6-9-7;/h7,9H,1-6H2;1H

Upstream product

• 1484-84-0 2(RS)-(2-hydroxyethyl)piperidine 
• 103-74-2 2-(2-Hydroxyethyl)pyridine 
• 54160-32-6 α-methyl-2-piperidylcarbinol 

Downstream Products

• 134277-62-6 1-acetyl-2-(2-chloroethyl)piperidine 
• 134277-63-7 1-acetyl-6-(2-chloroethyl)-2-piperidinone 
• 134277-68-2 10-<2-(1-methylpiperidin-2-on-6-yl)ethyl>-2-methylthio-10H-phenothiazine-5-sulfoxide 
• 142154-41-4 10-<2-(1-methylpiperidin-2-on-6-yl)ethyl>-2-methylsulfonyl-10H-phenothiazine 
• 106939-04-2 10-<2-(1-methylpiperidin-2-on-6-yl)ethyl>-2-methylsulfonyl-10H-phenothiazine-5-sulfoxide 
• 134291-23-9 10-<2-(1-methylpiperidin-2-on-6-yl)ethyl>-2-methylsulfonyl-10H-phenothiazine-5-sulfone 
• 405315-50-6 alpha-(4-Bromophenyl)-2-(2-chloroethyl)-1-piperidineacetonitrile 

Relevant academic research and scientific papers

Fe(III)-Catalyzed Aerobic Intramolecular N-N Coupling of Aliphatic Azides with Amines

An Fe(III)-catalyzed intramolecular N-N coupling of aliphatic azidoamines that forms diverse five- and six-membered semisaturated diazoheterocycles using air as an oxidant is reported, providing an alternative to hydrazine-based methods. Mechanistic studies suggest that a N-radical induced intramolecular homolytic substitution (SH2) is involved in ring closure. The power of this N-N bond-forming method is also demonstrated by using it as the final step in a total synthesis of (-)-newbouldine.

Synthesis of Different Classes of Six-Membered Gold(I) NHC Complexes by the Isonitrile Route

Different types of six-membered N-heterocyclic gold carbene complexes were prepared by using gold(I) isonitrile complexes as precursors in combination with suitably functionalized amines. The simple procedures provide an easy access to not only unsymmetrically substituted saturated carbene complexes but rarely reported types of carbene complexes such as six-membered N-heterocyclic oxo-carbene complexes, and six-membered partly unsaturated ligands can be obtained following the strategy.

Octahydro-indolizine and quinolizine and hexahydro-pyrrolizine

The invention features substituted fused bicyclic compounds, pharmaceutical compositions containing them, and methods of using them to treat or prevent histamine-mediated diseases and conditions.

3-diphenyl substituted octahydroindolizine analgesic compounds

Octahydroindolizine compounds of formula (I): STR1 wherein Q is --NR--, --(CH2)z --, --CH=CH--, --C C--, --OCH2 --, --SCH2 --, --SO2 --, --SO--, --CO--, or an oxygen or a sulfur atom and where R, R1 and R2 are substituents such as alkyl and x, y and z are independently the integers 0-3. Also, pharmaceutical compositions containing (I), intermediates and methods for treating pain.