60013-36-7Relevant academic research and scientific papers
Sterically Hindered N-Heterocyclic Salts Utilized as Antimicrobial Agents
Ndlovu, Slindile N. P.,Ibrahim, Halliru,Bala, Muhammad D.
, p. 3646 - 3655 (2017)
By the adoption of annulated ring systems for their steric bulkiness, a new series of symmetric N-heterocyclic imidazolium and perimidium salts were synthesized. Also, corresponding asymmetric ferrocenyl N-functionalized series were prepared as salts. All
Novel derivatives of the antibiotic NHC–Ag(I) drug candidate SBC3: Synthesis, biological evaluation and 109Ag NMR studies
O'Beirne, Cillian,Althani, Hessah T.,Dada, Oyinlola,Cassidy, Jennifer,Kavanagh, Kevin,Müller-Bunz, Helge,Ortin, Yannick,Zhu, Xiangming,Tacke, Matthias
, p. 95 - 103 (2018/05/22)
The synthesis of six novel N-heterocyclic carbene silver(I) acetate complexes, three symmetrical and three non-symmetrical, were achieved using 4,5-diphenylimidazole to produce intermediate imidazolium salts and then obtain the corresponding silver(I) com
TRIAZOLIUM AND IMIDAZOLIUM SALTS AND USES THEREOF
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Page/Page column 30-31, (2011/10/31)
The present disclosure relates to certain new and known triazolium and/or imidazolium salts and to their therapeutic use, for example in methods of treating or preventing an infection by a Plasmodium or Babesia parasite in a subject in need thereof. The triazolium and imidazolium salts are compounds of the Formula (I) or (II): wherein R1-R4, R1′-R3′, R8-R11, X, X′, X″, Y, Y′ and Y″ are as defined in the disclosure.
PLATINUM-N-HETEROCYCLIC CARBENE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF
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Page/Page column 22, (2011/08/02)
The invention relates to the platinum N-heterocycle derivatives of general formula (I) in which—R1 and/or R2 are, independently of one another, an aryl or aralkyl group, each optionally substituted, a linear or branched C1-C6 alkyl group, a monocyclic C3-C7 cycloalkyl group or a linear or branched C2-C6 alkenyl group, or else R′ is a hydrogen atom and R is a group selected from the following groups: cycloalkyl or heterocycloalkyl, which is monocyclic or bicyclic and has from 3 to 8 carbon atoms, or benzyl, which is optionally substituted, or else R and R′ form, together with NH, a C3-C8 monocyclic or bicyclic heterocycloalkyl, V is a nitrogen atom or a C—R4 radical, R3 and/or R4 are hydrogen or a phenyl group or R3 and R4 may also together form a C3-C6 alkylene radical or a C3-C6 heteroalkylene radical with one or more nitrogenous heteroatoms, it being possible for the carbon atoms of the heteroalkylene radical to be modified in the form of a carbonyl radical, and X is iodine, bromine, chlorine or a nitrato (—ONO2) group.
Synthesis of 2-imidazolones and 2-iminoimidazoles
Lima, Heather M.,Lovely, Carl J.
supporting information; experimental part, p. 5736 - 5739 (2011/12/05)
Convenient methods for the direct conversion of imidazolium salts to the corresponding 2-imidazolone or 2-imino imidazole derivatives have been developed. Treatment of the salt with commercial bleach leads to effective oxidation at C2 and the formation of the corresponding imidazolone. Alternatively, treatment of the salt with an N-chloro amide affords the corresponding protected 2-amino derivative in good yield.
