600134-66-5

Usage

Uses

Used in Pharmaceutical Industry:
(5-Methoxy-2-methyl-4-thiocyanatophenoxy)acetic acid methyl ester is used as a pharmaceutical compound for its potential therapeutic properties. Its unique structure with a methoxy, methyl, and thiocyanate group may contribute to its bioactivity and efficacy in treating various diseases.
Used in Agriculture:
(5-Methoxy-2-methyl-4-thiocyanatophenoxy)acetic acid methyl ester is used as an agrochemical compound for its potential applications in crop protection and enhancement. Its chemical properties may provide benefits in pest control, weed management, or plant growth regulation.
Used in Material Science:
(5-Methoxy-2-methyl-4-thiocyanatophenoxy)acetic acid methyl ester is used as a material science compound for its potential applications in the development of new materials with unique properties. Its chemical structure may contribute to the creation of innovative materials with applications in various industries.

Upstream product

• 540-72-7 sodium thiocyanide 
• 600134-65-4 5-Methoxy-2-methyl-4-thiocyanato-phenol 
• 96-32-2 bromoacetic acid methyl ester 
• 20734-74-1 5-methoxy-2-methyl-phenol 

Downstream Products

• 600134-67-6 (4-Mercapto-5-methoxy-2-methyl-phenoxy)-acetic Acid Methyl Ester 
• 613239-69-3 {5-Methoxy-2-methyl-4-[4-(4-trifluoromethyl-benzyloxy)-benzylsulfanyl]-phenoxy}-acetic Acid Methyl Ester 

Relevant academic research and scientific papers

Discovery of highly potent and selective benzyloxybenzyl-based peroxisome proliferator-activator receptor (PPAR) δ agonists

A series of 1,4-benzyloxybenzylsulfanylaryl carboxylic acids were prepared and their activities for PPAR receptor subtypes (α, δ, and γ) with potential indications for the treatment of dyslipidemia were investigated. Analog 13a displayed the greatest binding affinity (IC50 = 10 nM) and selectivity (120-fold) for PPARδ over PPARα. Many of the analogs investigated were found to be highly selective for PPARδ and were dependent on the point of attachment of the substituent. In the 1,4-series, analog 28e was found to be the most potent (IC50 = 1.7 nM) and selective (>1000-fold) compound for PPARδ. None of the compounds tested showed appreciable binding affinity for PPARγ.

Compounds that modulate PPAR activity and methods of preparation

This invention relates to compounds that alter PPAR activity. The invention also relates to pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the compounds or their salts, and methods of using them as therapeutic agents for treating or preventing dyslipidemia, hypercholesterolemia, obesity, hyperglycemia, atherosclerosis, hypertriglyceridemia and hyperinsulinemia in a mammal. The present invention also relates to methods for making the disclosed compounds.

Compounds that modulate PPAR activity and methods for their preparation

This invention discloses compounds that alter PPAR activity. The invention also discloses pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the compounds or their salts, and methods of using them as therapeutic agents for treating or preventing disipidemia, hypercholesteremia, obesity, eating disorders, hyperglycemia, atherosclerosis, hypertriglyceridemia, hyperinsulinemia and diabetes in a mammal as well as methods of supressing appetite and modulating leptin levels in a mammal. The present invention also discloses methods for making the disclosed compounds.

Compounds that modulate PPAR activity and methods of preparation

This invention discloses compounds that alter PPAR activity. The invention also discloses pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the compounds or their salts, and methods of using them as therapeutic agents for treating or preventing hyperlipidemia and hypercholesteremia in a mammal. The present invention also discloses methods for making the disclosed compounds.