600143-16-6Relevant articles and documents
Inhibition of group IVA cytosolic phospholipase A2 by novel 2-oxoamides in vitro, in cells, and in vivo
Kokotos, George,Six, David A.,Loukas, Vassilios,Smith, Timothy,Constantinou-Kokotou, Violetta,Hadjipavlou-Litina, Dimitra,Kotsovolou, Stavroula,Chiou, Antonia,Beltzner, Christopher C.,Dennis, Edward A.
, p. 3615 - 3628 (2007/10/03)
The Group IVA cytosolic phospholipase A2 (GIVA PLA2) is a particularly attractive target for drug development because it is the rate-limiting provider of proinflammatory mediators. We previously reported the discovery of novel 2-oxoa