600174-98-9

Upstream product

• 6746-94-7 Cyclopropylacetylene 
• 615-41-8 2-iodochlorobenzene 

Downstream Products

• 1196069-62-1 2-cyclopropyl-1-(2,6-di-iso-propylphenyl)-1H-indole 
• 1196069-61-0 2-cyclopropyl-1-(2,4,6-trimethylphenyl)-1H-indole 
• 1208119-82-7 (E)-N-[2-(2-chlorobenzylidene)cyclobutyl]-4-methylbenzenesulfonamide 
• 608131-07-3 [2-(2-chloro-phenyl)-1-cyclopropyl-ethyl]-hexyl-amine 
• 608131-06-2 tert-butyl-[2-(2-chloro-phenyl)-1-cyclopropyl-ethyl]-amine 

Relevant academic research and scientific papers

BAX INHIBITORS AND USES THEREOF

A compound having formula (I) or (II) for use inhibiting Bax mediated cell death and/or apoptosis.

Gold(l)-catalyzed ring expansions of unactivated alkynylcyclopropanes to (E)-2-alkylidenecyclobutanamines in the presence of sulfonamides

(Chemical Equation Presented) The ring expansion of cyclopropane derivatives provides a powerful method to construct synthetically useful four-membered carbocycles. Herein, a new type of gold(l)-catalyzed ring expansion of an unactivated alkynylcyclopropane/sulfonamide trapping strategy to (E)-2-alkylidenecyclobutanamines was described. The reaction tolerates a range of aryl and alkyl substituents with moderate to good yields.

A flexible synthesis of indoline, indolizidine, and pyrrolizidine derivatives

New and flexible procedures for the synthesis of indoline, indolizidine, and pyrrolizidine derivatives are described. By these new procedures, the target compounds can be synthesized with high diversity from three building blocks (ortho-bromo- or ortho-ch