60018-36-2

Basic information

• Product Name: Sulindac Acyl-β-D-Glucuronide
• Synonyms: Sulindac-acyl-beta-D-glucuronide min. 95%;Sulindac Acyl-β-D-Glucuronide
• CAS NO: 60018-36-2
• Molecular Formula: C26H25FO9S
• Molecular Weight: 532.5347032
• Product Categories: Pharmaceuticals;Sulfur & Selenium Compounds;Aromatics;Glucuronides;Intermediates & Fine Chemicals;Metabolites & Impurities
• Mol File: 60018-36-2.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: Sulindac Acyl-β-D-Glucuronide(CAS DataBase Reference)
• NIST Chemistry Reference: Sulindac Acyl-β-D-Glucuronide(60018-36-2)
• EPA Substance Registry System: Sulindac Acyl-β-D-Glucuronide(60018-36-2)

Safety Data

• Hazardous Substances Data: 60018-36-2(Hazardous Substances Data)

Usage

Description

Sulindac Acyl-β-D-Glucuronide is a significant metabolite derived from the non-steroidal anti-inflammatory drug Sulindac (S699215), which is primarily found in plasma and urine. This metabolite plays a crucial role in the therapeutic effects of the parent drug, contributing to its anti-inflammatory and analgesic properties.

Uses

Used in Pharmaceutical Industry:
Sulindac Acyl-β-D-Glucuronide is used as a metabolite for the non-steroidal anti-inflammatory drug Sulindac (S699215). It is responsible for the drug's anti-inflammatory and analgesic effects, making it an essential component in the treatment of various pain and inflammation-related conditions.
Used in Research and Development:
Sulindac Acyl-β-D-Glucuronide serves as a valuable compound in the research and development of new anti-inflammatory and analgesic drugs. Its study can provide insights into the mechanisms of action, pharmacokinetics, and potential side effects of Sulindac and similar drugs, leading to the development of more effective and safer medications.
Used in Drug Metabolism Studies:
As a major metabolite of Sulindac, Sulindac Acyl-β-D-Glucuronide is used in drug metabolism studies to understand how the body processes and eliminates the parent drug. This information is crucial for optimizing drug dosages, minimizing side effects, and ensuring the safe and effective use of the medication.
Used in Quality Control and Standardization:
Sulindac Acyl-β-D-Glucuronide is utilized in the quality control and standardization of pharmaceutical products containing Sulindac. Its presence and concentration in the final product can be used to ensure the consistency, efficacy, and safety of the drug, helping to maintain high-quality standards in the pharmaceutical industry.