600553-76-2Relevant academic research and scientific papers
1H-imidazo[4,5-c]quinoline derivatives as novel potent TNF-α suppressors: Synthesis and structure-activity relationship of 1-, 2-and 4-substituted 1H-imidazo[4,5-c]quinolines or 1H-imidazo[4,5-c]pyridines
Izumi, Tomoyuki,Sakaguchi, Jun,Takeshita, Makoto,Tawara, Harumi,Kato, Ken-Ichi,Dose, Hitomi,Tsujino, Tomomi,Watanabe, Yoshinari,Kato, Hideo
, p. 2541 - 2550 (2007/10/03)
Structural modification of imiquimod (1), which is known as an interferon-α (IFN-α) inducer, for the aim of finding a novel and small-molecule tumor necrosis factor-α (TNF-α) suppressor and structure-activity relationship (SAR) are described. Structural m
