60066-35-5 Usage
Uses
Used in Pharmaceutical Industry:
(3aR,10Z)-10-(hydroxymethyl)-6-methyl-3-methylidene-2,7-dioxo-2,3,3a,4,5,6,7,11a-octahydro-6,9-epoxycyclodeca[b]furan-4-yl 2-methylprop-2-enoate is used as a potential pharmaceutical compound for its unique structure that may offer various therapeutic applications. The presence of multiple functional groups and rings in the molecule suggests it could be further modified or utilized in the development of new drugs targeting specific biological pathways.
Used in Chemical Synthesis:
In the chemical industry, (3aR,10Z)-10-(hydroxymethyl)-6-methyl-3-methylidene-2,7-dioxo-2,3,3a,4,5,6,7,11a-octahydro-6,9-epoxycyclodeca[b]furan-4-yl 2-methylprop-2-enoate can be used as a building block or intermediate in the synthesis of more complex molecules. Its diverse functional groups make it a versatile starting material for creating a variety of chemical products, including specialty chemicals, materials, and other advanced compounds.
Used in Material Science:
The unique structure of (3aR,10Z)-10-(hydroxymethyl)-6-methyl-3-methylidene-2,7-dioxo-2,3,3a,4,5,6,7,11a-octahydro-6,9-epoxycyclodeca[b]furan-4-yl 2-methylprop-2-enoate may also find applications in material science. Its potential use could range from being a component in the development of new polymers with specific properties to being part of advanced materials with applications in various industries, such as electronics, aerospace, or automotive.
Check Digit Verification of cas no
The CAS Registry Mumber 60066-35-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,0,6 and 6 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 60066-35:
(7*6)+(6*0)+(5*0)+(4*6)+(3*6)+(2*3)+(1*5)=95
95 % 10 = 5
So 60066-35-5 is a valid CAS Registry Number.
60066-35-5Relevant academic research and scientific papers
Identification of a Covalent Importin-5 Inhibitor, Goyazensolide, from a Collective Synthesis of Furanoheliangolides
Barluenga, Sofia,Liu, Weilong,Loewith, Robbie,Patouret, Rémi,Plank, Michael,Winssinger, Nicolas
, p. 954 - 962 (2021/06/28)
Sesquiterpenes are a rich source of covalent inhibitors with a long history in traditional medicine and include several important therapeutics and tool compounds. Herein, we report the total synthesis of 16 sesquiterpene lactones via a build/couple/pair strategy, including goyasensolide. Using an alkyne-tagged cellular probe and proteomics analysis, we discovered that goyazensolide selectively targets the oncoprotein importin-5 (IPO5) for covalent engagement. We further demonstrate that goyazensolide inhibits the translocation of RASAL-2, a cargo of IPO5, into the nucleus and perturbs the binding between IPO5 and two specific viral nuclear localization sequences.
