60066-86-6Relevant academic research and scientific papers
Total Synthesis of the Macrocyclic Diterpene (-)-Casbene, The Putative Biogenetic Precursor of Lathyrane, Tigliane, Ingenane, and Related Terpenoid Structures
Crombie, Leslie,Kneen, Geoffrey,Pattenden, Gerald,Whybrow, Derek
, p. 1711 - 1717 (2007/10/02)
A total synthesis of the bicyclic diterpene 1S,3R(-)-casbene (19), based on elaboration of 1R,3S(+)-cis-chrystanthemic acid (21) to the bis-allylic bromide (20), followed by closure of the 14-membered ring with tetracarbonylnickel, is described.Sy
