600713-75-5Relevant academic research and scientific papers
Synthesis of the first examples of A-C8/C-C2 amide-Linked pyrrolo[2,1-c][1,4]benzodiazepine dimers
Gregson, Stephen J.,Howard, Philip W.,Thurston, David E.
, p. 2277 - 2280 (2003)
We report the synthesis of novel A-C8/C-C2 amide-linked pyrrolo[2,1-c][1,4]benzodiazepine dimers (4a and 4b) via convergent routes. These compounds lack the potent DNA interstrand cross-linking ability and resultant pronounced cytotoxicity of the known A-
