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600721-44-6

2,6-Piperidinedione, 3-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-1-(phenylmethoxy)- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 2,6-Piperidinedione, 3-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-1-(phenylmethoxy)-

    Cas No: 600721-44-6

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  • 600721-44-6 Structure

  • Basic information

    1. Product Name: 2,6-Piperidinedione, 3-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-1-(phenylmethoxy)-
    2. Synonyms:
    3. CAS NO:600721-44-6
    4. Molecular Formula: C20H18N2O4
    5. Molecular Weight: 350.374
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 600721-44-6.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2,6-Piperidinedione, 3-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-1-(phenylmethoxy)-(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2,6-Piperidinedione, 3-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-1-(phenylmethoxy)-(600721-44-6)
    11. EPA Substance Registry System: 2,6-Piperidinedione, 3-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-1-(phenylmethoxy)-(600721-44-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 600721-44-6(Hazardous Substances Data)

600721-44-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 600721-44-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,0,0,7,2 and 1 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 600721-44:
(8*6)+(7*0)+(6*0)+(5*7)+(4*2)+(3*1)+(2*4)+(1*4)=106
106 % 10 = 6
So 600721-44-6 is a valid CAS Registry Number.

600721-44-6Relevant articles and documents

Thalidomide metabolites and analogues. 3. Synthesis and antiangiogenic activity of the teratogenic and TNFα-modulatory thalidomide analogue 2-(2,6-dioxopiperidine-3-yl)phthalimidine

Luzzio, Frederick A.,Mayorov, Alexander V.,Ng, Sylvia S. W.,Kruger, Erwin A.,Figg, William D.

, p. 3793 - 3799 (2007/10/03)

Versatile synthesis of the teratogenic, TNFα-modulatory, and antiangiogenic thalidomide analogue 2-(2,6-dioxopiperidine-3-yl)phthalimidine (1) and its direct antiangiogenic properties are described. With thalidomide or thalidomide derivatives as precursors, the synthesis involved either carbonyl reduction/thiation-desulfurization or carbonyl reduction/acyliminium ion reduction protocols. Compared to earlier studies with thalidomide, which was only active with microsomal treatment, 1 exhibited marginal inhibitory activity in the rat aortic ring assay, thereby demonstrating the requirement for metabolic activation.

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