600726-61-2

Basic information

• Product Name: 3-Pyridinecarboxamide, 2,6-dichloro-N-(2-phenoxyethyl)-
• CAS NO: 600726-61-2
• Molecular Formula: C14H12Cl2N2O2
• Molecular Weight: 311.167
• Mol File: 600726-61-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Pyridinecarboxamide, 2,6-dichloro-N-(2-phenoxyethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarboxamide, 2,6-dichloro-N-(2-phenoxyethyl)-(600726-61-2)
• EPA Substance Registry System: 3-Pyridinecarboxamide, 2,6-dichloro-N-(2-phenoxyethyl)-(600726-61-2)

Safety Data

• Hazardous Substances Data: 600726-61-2(Hazardous Substances Data)

Upstream product

• 58584-83-1 2,6-dichloronicotinoyl chloride 
• 1758-46-9 2-phenoxyethanamine 

Downstream Products

• 802916-69-4 C₂₁H₂₀ClN₃O₄ 
• 802916-68-3 C₂₃H₂₃ClN₂O₅ 

Relevant articles and documents

Discovery and structure-activity relationships of trisubstituted pyrimidines/pyridines as novel calcium-sensing receptor antagonists

The trisubstituted pyrimidine 1 was identified through high-throughput screening as a novel calcium-sensing receptor (CaSR) antagonist. Small molecule CaSR antagonists and/or negative allosteric modulators have the potential to act as an anabolic agent for the treatment of osteoporosis. The investigation of structure-activity relationships around 1 resulted in the identification of 18c and 18d, which showed efficacy at promoting PTH release in vivo and exhibited improved potency and solubility over the original lead 1.