600727-42-2Relevant academic research and scientific papers
Intramolecular cyclization of δ-iminoacetylenes: A new entry to pyrazino[1,2-a]indoles
Abbiati, Giorgio,Arcadi, Antonio,Bellinazzi, Alessandra,Beccalli, Egle,Rossi, Elisabetta,Zanzola, Simona
, p. 4088 - 4095 (2005)
The synthesis of the pyrazino[1,2-a]indole nucleus was achieved by intramolecular cyclization of several 2-carbonyl-1-propargylindoles in the presence of ammonia. The reaction conditions were optimized using microwave heating and a pool of catalysts. Cycl
Novel intramolecular cyclization of N-alkynyl heterocycles containing proximate nucleophiles
Abbiati, Giorgio,Arcadi, Antonio,Beccalli, Egle,Rossi, Elisabetta
, p. 5331 - 5334 (2007/10/03)
Intramolecular cyclization of 2-acyl-1-propargyl-1H-indoles in the presence of ammonia provides an easy entry to pyrazino[1,2-a]indole nucleus.
