6008-51-1Relevant articles and documents
Synthesis of common-sized heterocyclic compounds by intramolecular cyclization over halide cluster catalysts
Nagashima, Sayoko,Sasaki, Tomoaki,Kamiguchi, Satoshi,Chihara, Teiji
supporting information, p. 764 - 766 (2015/06/22)
Five- to seven-membered common-sized heterocyclic compounds containing an oxygen, sulfur, or nitrogen were synthesized by the intramolecular condensation of α,ω-hydroxy, mercapto, or amino alkanes, respectively, over halide cluster complexes as a thermally stable molecular solid weak acid catalyst in the gas phase at temperatures ≥150 °C. From ω- mercapto and ω-amino alcohols, cyclic sulfides and amines were obtained, respectively. These unimolecular reactions are thermodynamically and kinetically favored.
The macrocyclization reaction of terminal dibromoalkanes with sulfide on alumina. The use of a solid support as an alternative to the high dilution technique
Tan,Pagni,Kabalka,Hillmeyer,Woosley
, p. 7709 - 7712 (2007/10/02)
The reaction of a series of terminal dibromoalkanes with S-2 on Al2O3 has been examined. The use of a solid support for the macrocyclization represents a viable alternate procedure to the more traditional high dilution technique in solution. The cyclization also occur with thioacetamide on unactivated alumina.
