60090-80-4Relevant academic research and scientific papers
Tandem double-intramolecular [4+2]/[3+2] cycloadditions of nitroalkenes. Studies toward a total synthesis of daphnilactone B: Piperidine ring construction
Denmark, Scott E.,Baiazitov, Ramil Y.
, p. 593 - 605 (2006)
Two model studies in support of a total synthesis of the complex polycyclic alkaloid daphnilactone B have been completed. The objectives of the models studies were to demonstrate the use of a tandem double-intramolecular [4+2]/[3+2] nitroalkene cycloaddit
Stereoselective Synthesis of Alcohols, XLIII. Asymmetric Induction on the Intramolecular Allylboration Reaction of (8-Oxo-2-octenyl)boronates
Hoffmann, Reinhard W.,Sander, Thomas
, p. 1185 - 1192 (2007/10/02)
The cyclization of (8-oxo-2-octenyl)boronates having methyl substituents in the chain linking the two functional groups proceeds with complete simple diastereoselectivity and with induced diastereoselectivity of 85 to >98percent to give methyl-substituted 2-vinylcyclohexanols. - Key Words: Cyclization, stereoselective / Allylboration, intramolecular / Boronates
Stereoselective Synthesis of Alcohols, XLII. Stereoselective Cyclization of (8-Oxo-2-octenyl)boronates to cis- or trans-Vinylcyclohexanol
Hoffmann, Reinhard W.,Sander, Thomas,Hense, Achim
, p. 771 - 776 (2007/10/02)
Intramolecular allylboration reactions of (8-oxo-2-octenyl)boronates proceed with excellent diastereoselectivity: the E-isomer 1d leads to the trans-2-vinylcyclohexanol (2) with 99.5percent d.s., the corresponding Z-isomer 3d cyclizes to give the cis-isomer with a diastereoselectivity exceeding 99.8percent.Key Words: Cylization, stereoselective / Allylboration, intramolecular
