60092-32-2

Basic information

• Product Name: (Hexahydro-2,4-methano-4H-furo[3,2-b]pyrrol-3-yl)methylcarbamic acid [6-acetylamino-4-chloro-1-azabicyclo[3.3.0]octan-7-yl] ester
• Synonyms: (Hexahydro-2,4-methano-4H-furo[3,2-b]pyrrol-3-yl)methylcarbamic acid [6-acetylamino-4-chloro-1-azabicyclo[3.3.0]octan-7-yl] ester;Lolidine
• CAS NO: 60092-32-2
• Molecular Formula: C18H27ClN4O4
• Molecular Weight: 398.88
• Mol File: 60092-32-2.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 594.3±50.0 °C(Predicted)
• Appearance: /
• Density: 1.42±0.1 g/cm3(Predicted)
• PKA: 14.37±0.60(Predicted)
• CAS DataBase Reference: (Hexahydro-2,4-methano-4H-furo[3,2-b]pyrrol-3-yl)methylcarbamic acid [6-acetylamino-4-chloro-1-azabicyclo[3.3.0]octan-7-yl] ester(CAS DataBase Reference)
• NIST Chemistry Reference: (Hexahydro-2,4-methano-4H-furo[3,2-b]pyrrol-3-yl)methylcarbamic acid [6-acetylamino-4-chloro-1-azabicyclo[3.3.0]octan-7-yl] ester(60092-32-2)
• EPA Substance Registry System: (Hexahydro-2,4-methano-4H-furo[3,2-b]pyrrol-3-yl)methylcarbamic acid [6-acetylamino-4-chloro-1-azabicyclo[3.3.0]octan-7-yl] ester(60092-32-2)

Safety Data

• Hazardous Substances Data: 60092-32-2(Hazardous Substances Data)

Usage

Description

Russian workers have recently re-examined the alkaloidal extract of the seeds of Lotium cuneatum and shown that, in addition to a number of simple pyrrolizidine bases, it also contains this novel dimeric alkaloid. Lolidine is one of the few bases found in this plant which contains chlorine in the molecule. The base may be separated from the total alkaloids on a silica gel column from Et20 solution. Treatment with either Ac20 or AcCl fails to give the acetyl derivative confirming that the fourth oxygen atom is present in the form of an ether bridge.

References

Batirov, Malikov, Yunusov, Khim. Prir. Soedin., 12,63 (1976)