60103-01-7 Usage
Uses
Used in Pharmaceutical Industry:
(R)-2-AMINO-3-METHYL-BUT-3-ENOIC ACID HCL is used as a building block for the synthesis of peptides and pharmaceuticals due to its chiral nature and biological activity. Its unique structure allows for the creation of novel drugs with potential applications in treating a range of medical conditions.
Used in Drug Development:
(R)-2-AMINO-3-METHYL-BUT-3-ENOIC ACID HCL is used as a key component in the development of new drugs and treatments. Its HCL salt form provides better solubility and stability, making it more suitable for pharmaceutical applications and potentially leading to the discovery of innovative therapies for various diseases.
Used in Research and Development:
(R)-2-AMINO-3-METHYL-BUT-3-ENOIC ACID HCL is utilized as a research compound for studying its properties and potential applications in the field of medicinal chemistry. Its unique structure and biological activity make it an interesting candidate for further investigation and development of new therapeutic strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 60103-01-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,1,0 and 3 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 60103-01:
(7*6)+(6*0)+(5*1)+(4*0)+(3*3)+(2*0)+(1*1)=57
57 % 10 = 7
So 60103-01-7 is a valid CAS Registry Number.
60103-01-7Relevant academic research and scientific papers
Synthesis of optically active β,γ-unsaturated α-amino acids of α,β-unsaturated γ-amino acids. S(N)2- vs. S(N)2'-dichotomy of the Mitsunobu amination of allylic alcohols
Mulzer,Funk
, p. 101 - 112 (2007/10/02)
Novel and efficient syntheses (6-9 steps, overall yields 10-30%) are described for optically pure β,γ-unsaturated α-amino acids and α,β-unsaturated γ-amino acids, starting from (R)-isopropylidene glyceraldehyde and ethyl (S)-lactate, respectively. The key step is the Mitsunobu reaction of chiral secondary allylic alcohols with phthalimide as the nucleophile, where α,γ allylic transpositions are observed for the first time. The structure-α,γ-ratio-relationship is studied and also the stereochemistry of the allylic transposition. The α-substitution proceeds via clean S(N)2 inversion, whereas the γ-substitution corresponds to an (E)-anti attack of the nucleophilic with varying stereoselectivities.
