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WITHASTRAMONOLIDE, 12-DEOXY-(SH) is a derivative of Withaferin-A, a naturally occurring steroid lactone found in the plant Withania somnifera, commonly known as Ashwagandha. It possesses promising anticancer properties and has demonstrated cytotoxic activity against various cancer cell lines, making it a potential candidate for the development of novel therapeutic agents for cancer treatment. Furthermore, it has also shown anti-inflammatory and neuroprotective effects, highlighting its versatility in addressing various disease conditions.

60124-17-6

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60124-17-6 Usage

Uses

Used in Pharmaceutical Industry:
WITHASTRAMONOLIDE, 12-DEOXY-(SH) is used as an anticancer agent for its cytotoxic activity against various cancer cell lines. It has the potential to be developed into a novel therapeutic agent for the treatment of cancer, offering a promising alternative for cancer patients.
Used in Anti-inflammatory Applications:
WITHASTRAMONOLIDE, 12-DEOXY-(SH) is used as an anti-inflammatory agent due to its demonstrated anti-inflammatory effects. It can be utilized in the development of treatments for inflammatory conditions, providing relief and managing inflammation in various disease states.
Used in Neuroprotective Applications:
WITHASTRAMONOLIDE, 12-DEOXY-(SH) is used as a neuroprotective agent for its ability to protect neurons and reduce neuronal damage. It can be employed in the development of therapies for neurodegenerative diseases, aiming to preserve cognitive function and improve the quality of life for patients.

Check Digit Verification of cas no

The CAS Registry Mumber 60124-17-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,1,2 and 4 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 60124-17:
(7*6)+(6*0)+(5*1)+(4*2)+(3*4)+(2*1)+(1*7)=76
76 % 10 = 6
So 60124-17-6 is a valid CAS Registry Number.

60124-17-6 Well-known Company Product Price

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  • Sigma-Aldrich

  • (94187)  12-Deoxywithastramonolide  analytical standard

  • 60124-17-6

  • 94187-10MG

  • 6,873.75CNY

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60124-17-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 12-Deoxywithastramonolide

1.2 Other means of identification

Product number -
Other names 27-Hydroxywithanolide B

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:60124-17-6 SDS

60124-17-6Downstream Products

60124-17-6Relevant academic research and scientific papers

Baimantuoluosides A-C, three new withanolide glucosides from the flower of Datura metel L.

Kuang, Haixue,Yang, Bingyou,Tang, Ling,Xia, Yonggang,Dou, Deqiang

experimental part, p. 1315 - 1323 (2009/10/17)

In search for bioactive compounds from the flower of Datura metel L., three new withanolide glucosides, namely baimantuoluosides A, B, and C (1-3, resp.) were isolated. Enzymatic hydrolysis of 1-3 afforded the corresponding aglycones 1a, 2a, and 3a, respectively. The structures of the new compounds were elucidated as (5α,6α,7α,12β,22R)-5,12-dihydroxy-1,26- dioxo-6,7:22,26-diepoxyergosta-2,24-dien-27-yl β-D-glucopyranoside (1), (5α,6α,7α,12α,22R)-5,12-dihydroxy-1,26-dioxo-6,7:22, 26-diepoxyergosta-2,24-dien-27-yl β-D-glucopyranoside (2), (5α,6α,7α,22R)-5-hydroxy-1,26-dioxo-6,7:22, 26-diepoxyergosta-2,24-dien-27-yl β-D-glucopyranoside (3) on the basis of chemical and physicochemical evidence, and are further confirmed by the structure determination by X-ray diffraction of withanolide aglycone 1a.

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