6014-30-8

Basic information

• Product Name: methyldopate
• Synonyms: methyldopa ethyl;methyldopate;ethyl 2-amino-3-(3,4-dihydroxyphenyl)-2-methyl-propanoate;Alanine, 3-(3,4-dihydroxyphenyl)-2-methyl-, ethyl ester, L-;L-3-(3,4-Dihydroxyphenyl)-2-methylalanine ethyl ester;SVEBYYWCXTVYCR-LBPRGKRZSA-N
• CAS NO: 6014-30-8
• Molecular Formula: C₁₂H₁₇NO₄
• Molecular Weight: 239.27
• Mol File: 6014-30-8.mol

Chemical Properties

• Boiling Point: 398°C at 760 mmHg
• Flash Point: 194.5°C
• Appearance: /
• Density: 1.243g/cm³
• Vapor Pressure: 6.62E-07mmHg at 25°C
• Refractive Index: 1.572
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly, Heated), Methanol (Slightly)
• PKA: 9.83±0.10(Predicted)
• Stability: Hygroscopic
• CAS DataBase Reference: methyldopate(CAS DataBase Reference)
• NIST Chemistry Reference: methyldopate(6014-30-8)
• EPA Substance Registry System: methyldopate(6014-30-8)

Safety Data

• Hazardous Substances Data: 6014-30-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Methyldopate is used as an antihypertensive agent for the treatment of hypertension. It is particularly effective in managing high blood pressure during pregnancy, as it has been shown to have minimal effects on the fetus. The hypotensive effects of methyldopate make it a valuable drug for managing various cardiovascular conditions.
Used in Oncology:
Methyldopate has been found to be effective in the treatment of murine neural blastoma, a type of cancer that affects the nervous system. Its application in oncology is still being researched, but the initial findings suggest that it may have potential as a therapeutic agent for certain types of cancer.

InChI:InChI=1/C12H17NO4/c1-3-17-11(16)12(2,13)7-8-4-5-9(14)10(15)6-8/h4-6,14-15H,3,7,13H2,1-2H3

Upstream product

• 64-17-5 ethanol 
• 555-30-6 methyldopa 
• 1395919-80-8 (S)-2-(1-naphthamido)-3-(benzo[d][1,3]dioxol-5-yl)-2-methylpropanoic acid 

Relevant articles and documents

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