601494-31-9 Usage
Uses
Used in Medicinal Chemistry and Drug Discovery:
1H-Imidazole, 2-(3-nitrophenyl)-5-(trifluoromethyl)is used as a building block for the synthesis of potential pharmaceutical compounds. Its unique structure and functional groups make it a valuable component in the development of new drugs and therapeutics.
Used in Organic Synthesis:
In the field of organic synthesis, 1H-Imidazole, 2-(3-nitrophenyl)-5-(trifluoromethyl)serves as a reagent in various chemical reactions. Its presence can facilitate the formation of desired products and improve the efficiency of synthetic processes.
Used in Biological and Pharmacological Research:
Due to its potential biological and pharmacological activities, 1H-Imidazole, 2-(3-nitrophenyl)-5-(trifluoromethyl)is a subject of interest in research aimed at discovering new drugs and therapeutics. Its properties may contribute to the development of treatments for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 601494-31-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,0,1,4,9 and 4 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 601494-31:
(8*6)+(7*0)+(6*1)+(5*4)+(4*9)+(3*4)+(2*3)+(1*1)=129
129 % 10 = 9
So 601494-31-9 is a valid CAS Registry Number.
601494-31-9Relevant academic research and scientific papers
Discovery of novel 2-aryl-4-bis-amide imidazoles (ABAI) as anti-inflammatory agents for the treatment of inflammatory bowel diseases (IBD)
Li, Ling,Yuan, Sijie,Lin, Lin,Yang, Fang,Liu, Ting,Xu, Chenglong,Zhao, Huiting,Chen, Jingxuan,Kuang, Peihua,Chen, Ting,Liao, Wenzhen,Chen, Jianjun
, (2022/01/28)
A series of 2-Aryl-4-Bis-amide Imidazoles (ABAI-1 to 30) were designed as anti-inflammatory agents. These compounds were synthesized and evaluated for the in vitro anti-inflammatory activities (inhibition of NO production and release of inflammatory cytok
Rigid macrocyclic triamides as anion receptors: Anion-dependent binding stoichiometries and 1H chemical shift changes
Choi, Kihang,Hamilton, Andrew D.
, p. 10241 - 10249 (2007/10/03)
The cyclic triamide of 3′-amino-3-biphenylcarboxlic acid is readily synthesized in a stepwise manner and represents a novel class of anion receptors with a large central cavity. This macrocycle binds more strongly to tetrahedral anions than spherical or p
