601513-26-2

Basic information

• Product Name: 2-CHLORO-4-(TRIFLUOROMETHYL)PHENYLACETIC ACID
• Synonyms: 2-CHLORO-4-(TRIFLUOROMETHYL)PHENYLACETIC ACID;2-(2-Chloro-4-(trifluoromethyl)phenyl)acetic acid;2-(2-Chloro-4-(trifluoromethyl)
• CAS NO: 601513-26-2
• Molecular Formula: C₉H₆ClF₃O₂
• Molecular Weight: 238.5909496
• Mol File: 601513-26-2.mol
• Article Data: 5

Chemical Properties

• Melting Point: 108-111℃
• Boiling Point: 282.2±35.0 °C(Predicted)
• Appearance: White/Powder
• Density: 1.469±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 3.76±0.10(Predicted)
• CAS DataBase Reference: 2-CHLORO-4-(TRIFLUOROMETHYL)PHENYLACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-4-(TRIFLUOROMETHYL)PHENYLACETIC ACID(601513-26-2)
• EPA Substance Registry System: 2-CHLORO-4-(TRIFLUOROMETHYL)PHENYLACETIC ACID(601513-26-2)

Safety Data

• Hazardous Substances Data: 601513-26-2(Hazardous Substances Data)

Usage

General Description

2-Chloro-4-(trifluoromethyl)phenylacetic acid is a chemical compound with the molecular formula C9H6ClF3O2. It is a derivative of phenylacetic acid and contains a chloro and trifluoromethyl group. 2-CHLORO-4-(TRIFLUOROMETHYL)PHENYLACETIC ACID is used in the pharmaceutical industry as a building block for the synthesis of various drugs and pharmaceuticals. It may also have potential applications in the field of agrochemicals. Due to its unique structure, 2-Chloro-4-(trifluoromethyl)phenylacetic acid has the potential to exhibit diverse chemical and biological properties, making it an interesting target for further research and development.

Upstream product

• 141738-80-9 2-chloro-1-iodo-4-(trifluoromethyl)benzene 
• 601513-27-3 2-chloro-4-(trifluoromethyl)phenylacetic acid tert-butyl-ester 
• 540-88-5 acetic acid tert-butyl ester 
• 213697-53-1 DavePhos 
• 76-05-1 trifluoroacetic acid 

Downstream Products

• 601513-28-4 3-(2-Chloro-4-trifluoromethylphenyl)-4-(4-hydroxybenzyl)-7-methoxy-chromen-2-one 
• 1134916-06-5 methyl 2-(2-chloro-4-(trifluoromethyl)phenyl)acetate 

Relevant articles and documents

HETEROCYCLIC AMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS

The invention relates to heterocyclic amide derivatives of formula (I), wherein R1, R2, R3, R4, R5, X, Y and n are as defined in the description, their preparation and their use as pharmaceutically active compounds.

BICYCLIC PYRIMIDIN-4-(3H)-ONES AND ANALOGUES AND DERIVATIVES THEREOF WHICH MODULATE THE FUNCTION OF THE VANILLOID-1 RECEPTOR (VR1)

Compounds of formula (I); which are useful as therapeutic compounds, particularly in the treatment of pain and other conditions ameliorated by the modulation of the function of the vanilloid-1 receptor (VR1).

Benzopyrazone compounds, compositions thereof, and methods of treatment therewith

Benzopyranone compounds having the following structure: wherein R1, X, Y and n are as defined here, are disclosed. The compounds of formula (I), wherein R1is H, can be prepared by demethylation of the corresponding phenolic methyl et