60164-99-0Relevant academic research and scientific papers
Stereochemistry of Transition-Metal-Catalyzed Cross-Coupling Reactions
Walborsky, H. M.,Banks, R. Bruce
, p. 5074 - 5077 (1981)
The stereochemical results of transition-metal-catalyzed cross-coupling of methyllithium with chiral (+)-(S)-(4-methylcyclohexylidene)bromomethane (1) are reported.The use of bis(triphenylphosphine) dichlorocobalt(II), iron(III) tris(dibenzoylmethide), and dichloronickel(II) yielded chiral 1-methyl-4-ethylidenecyclohexane (2) with 89percent, 96percent, and 96percent retention of configuration, respectively.By contrast, the use of silver bromide yielded totally racemic product.
