6017-71-6Relevant academic research and scientific papers
Total synthesis and mechanism of action of the antibiotic armeniaspirol A
Arisetti, Nanaji,Bafna, Jayesh A.,Bauer, Armin,Bhamidimarri, Satya P.,Br?nstrup, Mark,Coetzee, Janetta,Eckel, Konstantin,Fuchs, Hazel L. S.,Heimann, Dominik,Herrmann, Jennifer,Hinkelmann, Bettina,Kuhnert, Eric,Müller, Peter P.,Müller, Rolf,Orozco, Manuel,Ruppelt, Dominik,Sieber, Stephan A.,Steinem, Claudia,Winterhalter, Mathias
, p. 16023 - 16034 (2021/12/30)
Emerging antimicrobial resistance urges the discovery of antibiotics with unexplored, resistance-breaking mechanisms. Armeniaspirols represent a novel class of antibiotics with a unique spiro[4.4]non-8-ene scaffold and potent activities against Gram-posit
Armeniaspiroles, a new class of antibacterials: Antibacterial activities and total synthesis of 5-chloro-Armeniaspirole A
Couturier, Cedric,Bauer, Armin,Rey, Astrid,Schroif-Dufour, Cosima,Broenstrup, Mark
supporting information, p. 6292 - 6296 (2012/10/29)
Armeniaspiroles, a novel class of natural products isolated from Streptomyces armeniacus, are characterized by a novel spiro[4.4]non-8-ene scaffold. Various derivatives of Armeniaspiroles could be obtained by halogenation, alkylation, addition/elimination
Hydroxyacetophenone-derived antagonists of the peptidoleukotrienes
Brown,Bersntein,Cronk,Dossett,Hebbel,Maduskuie Jr.,Shapiro,Vacek,Yee,Willard,Krell,Snyder
, p. 807 - 826 (2007/10/02)
Considerations of the possible similarities between leukotriene D4 and its prototypical antagonist, FPL 55712, led to the development of a new series of leukotriene antagonists incorporating a hydroxyacetophenone group (e.g., the toluic acids 1
