60184-74-9Relevant academic research and scientific papers
Electrochemical bromofunctionalization of alkenes in a flow reactor
Seitz, Jakob,Wirth, Thomas
supporting information, p. 6892 - 6896 (2021/08/20)
The bromination of organic molecules has been extensively studied to date, yet there is still a demand for safe and sustainable methodologies. Hazardous reagents, selectivity, low atom economy and waste production are the most persisting problems of brominating reagents. The electrochemical oxidation of bromide to bromine is a viable strategy to reduce waste by avoiding chemical oxidants. Furthermore, thein situgeneration of reactive intermediates minimizes the risk of hazardous reagents. In this work, we investigate the electrochemical generation of bromine from hydrobromic acid in a flow electrochemical reactor. Various alkenes could be converted to their corresponding dibromides, bromohydrines, bromohydrin ethers and cyclized products in good to excellent yields.
Cycloallenes, 13. - Cyclohexa-1,2,4-triene from 1-bromocyclohexa-1,4- diene
Christl, Manfred,Groetsch, Stefan
, p. 1871 - 1874 (2007/10/03)
1-Bromocyclohexa-1,4-diene (3) was prepared from trans-4,5- dibromocyclohexene by elimination of hydrogen bromide. Treatment of a solution of 3 in furan or 2,5-dimethylfuran with KOtBu afforded the tetrahydroepoxynaphthalenes 4 and 5, respectively. The st
