60187-67-9 Usage
Uses
Used in Pharmaceutical Industry:
Dimethyl acetamidomalonate is used as a building block and versatile intermediate for the synthesis of various pharmaceutical products. Its ability to introduce different functional groups and stereochemistry makes it a valuable component in the development of new drugs.
Used in Organic Synthesis:
Dimethyl acetamidomalonate is used as a reagent in organic synthesis, contributing to the creation of complex molecules with specific functional groups and stereochemistry.
Used in the Synthesis of Biologically Active Molecules:
Dimethyl acetamidomalonate is used as a reagent in the synthesis of biologically active molecules, such as antitumor and antiviral agents, due to its ability to introduce desired functional groups and stereochemistry into these molecules.
Used in Drug Development:
Dimethyl acetamidomalonate has potential applications in the development of new drugs and pharmaceutical products, as its unique properties allow for the introduction of various functional groups and stereochemistry into complex molecules, enhancing their therapeutic effects and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 60187-67-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,1,8 and 7 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 60187-67:
(7*6)+(6*0)+(5*1)+(4*8)+(3*7)+(2*6)+(1*7)=119
119 % 10 = 9
So 60187-67-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H11NO5/c1-4(9)8-5(6(10)12-2)7(11)13-3/h5H,1-3H3,(H,8,9)
60187-67-9Relevant academic research and scientific papers
Reaction of Dicarbomethoxycarbene with Acetaldehyde and Simple Ketones
L'Esperance, Robert P.,Ford, Thomas M.,Jones, Maitland
, p. 209 - 213 (2007/10/02)
Singlet dicarbomethoxycarbene reacts with acetaldehyde to give dioxolane 8, the ultimate product of formation of ylide 10 and subsequent addition of a second molecule of aldehyde.Photosensitized generation of the carbene gives increased hydrogen abstraction and decreased products derived from the ylide.Replacement of the aldehyde with a ketone changes the course of the reaction and dioxolanes (11, 20, and 26) become the major products.Suggestions are made for the mechanisms of the singlet and triplet reactions and for the peculiar behavior of acetone in which generation of singlet and triplet carbene gives the same product slate.
