60211-73-6Relevant academic research and scientific papers
Synthesis of Sulfonylsubstituted Heterocycles by Cyclocondensation of Sulfones with Bifunctionalised Compounds
Lemcke, Thomas,Messinger, Paul
, p. 1 - 4 (1994)
2-Sulfonylketendithioacetales (1), alkyl-sulfonylacetates (6), 2-sulfonyl-acetophenones (9) and -nitriles (12) react by cyclocondensation with bifunctionalised compounds 2, 4, 7, 10 and 13 yielding the sulfonylsubstituted chinoline- 3, chinolone- 5, barbituric acid- 8, pyrane- 11 and coumarine 15 derivatives.
Synthesis and antioxidant and antitumor activity of novel pyridine, chromene, thiophene and thiazole derivatives
Fadda, Ahmed A.,Berghot, Moged A.,Amer, Fathy A.,Badawy, Doria S.,Bayoumy, Nesma M.
experimental part, p. 378 - 385 (2012/07/28)
2-Tosylacetonitrile (1) when reacted with α,β-unsaturated nitriles 2a-c or a mixture of formaldehyde and 3-amino-2-substituted-pent-2- endinitriles 6a,b yielded pyridine derivatives 3a-c and 9a,b, respectively, while when subjected to react with salicylal
Three-component coupling using arynes and DMF: Straightforward access to coumarins via ortho-quinone methides
Yoshida, Hiroto,Ito, Yu,Ohshita, Joji
supporting information; experimental part, p. 8512 - 8514 (2011/09/16)
ortho-Quinone methides, arising from a formal [2+2] cycloaddition between arynes and DMF, were found to facilely undergo a [4+2] cycloaddition with ester enolates or ketenimine anions to produce diverse coumarins in a straightforward manner. The Royal Society of Chemistry 2011.
Synthesis of 3-Coumaryl Phenyl Sulfones or Sulfoxides
Merchant, J.R.,,Shah, P.J.,
, p. 441 - 442 (2007/10/02)
An unambiguous synthesis of a number of 3-coumaryl phenyl sulfones or sulfoxides have been described which were obtained by the oxidation of the corresponding sulfides with hydrogen peroxide.The sulfides were prepared by the Perkin-Oglialore reaction of o-hydroxyaldehyde with the sodium salt of different S-phenyl thioacetic acids.The sulfones did not exhibit any appreciable antituberculous activity in the preliminary screening tests.
