60214-07-5

Basic information

• Product Name: 5-(4-bromophenyl)penta-2,4-diyn-1-ol
• Synonyms: 5-(4-bromophenyl)penta-2,4-diyn-1-ol
• CAS NO: 60214-07-5
• Molecular Weight: 235.08
• Mol File: 60214-07-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-(4-bromophenyl)penta-2,4-diyn-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-bromophenyl)penta-2,4-diyn-1-ol(60214-07-5)
• EPA Substance Registry System: 5-(4-bromophenyl)penta-2,4-diyn-1-ol(60214-07-5)

Safety Data

• Hazardous Substances Data: 60214-07-5(Hazardous Substances Data)

Upstream product

• 766-96-1 4-bromo-1-ethynylbenzene 
• 107-19-7 propargyl alcohol 
• 37614-58-7 3-(4-bromophenyl)prop-2-yn-1-ol 
• 589-87-7 1,4-bromoiodobenzene 
• 2060-25-5 3-bromoprop-2-yn-1-ol 

Downstream Products

• 60214-13-3 1-bromo-4-(1,3-butadiyn-1-yl)benzene 

Relevant articles and documents

Selective Hydroarylation of 1,3-Diynes Using a Dimeric Manganese Catalyst: Modular Synthesis of Z-Enynes

The transition-metal-catalyzed selective hydroarylation of unsymmetrical alkynes represents the state-of-art in organic chemistry, and still mainly relies on the use of precious late-transition-metal catalysts. Reported herein is an unprecedented MnI-catalyzed hydroarylation of unsymmetrical 1,3-diyne alcohols with commercially available arylboronic acids with predictive selectivity. This method addresses the challenges in regio-, stereo-, and chemoselectivity. It offers a general, convenient and practical strategy for the modular synthesis of multisubstituted Z-configurated conjugated enynes. This protocol is distinguished by its operational simplicity, complete selectivity, excellent functional-group compatibility, and gram-scale potential. A dimeric MnI species, Mn2(CO)8Br2, was proven to be a much more efficient catalyst precursor than Mn(CO)5Br.

Synthesis of Unsymmetrical 1,4-Diarylbutadiynes by Stille Coupling

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