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4-O-deacetylvinblastine-3-oic acid, also known as O4-Desacetyl Vinblastinic Acid, is an impurity derived from Vinblastine Sulfate (V314000), an antineoplastic alkaloid isolated from the periwinkle plant, Vinca rosea Linn., belonging to the Apocynaceae family. 4-O-deacetylvinblastine-3-oic acid possesses the ability to inhibit microtubule assembly, which is a crucial process in cell division, making it a significant pharmaceutical candidate in the field of cancer treatment.

60223-75-8

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60223-75-8 Usage

Uses

Used in Anticancer Applications:
4-O-deacetylvinblastine-3-oic acid is used as an antineoplastic agent for its ability to inhibit microtubule assembly, a critical process in cell division. By disrupting this process, it can effectively hinder the proliferation of cancer cells, making it a valuable component in the development of cancer treatment strategies.
Used in Pharmaceutical Research and Development:
In the pharmaceutical industry, 4-O-deacetylvinblastine-3-oic acid is used as a key compound in the research and development of novel antineoplastic drugs. Its unique properties and mechanisms of action provide a foundation for the creation of innovative therapies targeting various types of cancer.
Used in Drug Delivery Systems:
Similar to gallotannin, 4-O-deacetylvinblastine-3-oic acid can also be incorporated into drug delivery systems to enhance its bioavailability, delivery, and therapeutic outcomes. The development of advanced drug delivery systems, such as organic and metallic nanoparticles, can help improve the efficacy of 4-O-deacetylvinblastine-3-oic acid in cancer treatment by ensuring its targeted and controlled release to the affected cells.

Check Digit Verification of cas no

The CAS Registry Mumber 60223-75-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,2,2 and 3 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 60223-75:
(7*6)+(6*0)+(5*2)+(4*2)+(3*3)+(2*7)+(1*5)=88
88 % 10 = 8
So 60223-75-8 is a valid CAS Registry Number.
InChI:InChI=1/C43H54N4O8/c1-6-39(52)21-25-22-42(38(51)55-5,33-27(13-17-46(23-25)24-39)26-11-8-9-12-30(26)44-33)29-19-28-31(20-32(29)54-4)45(3)35-41(28)15-18-47-16-10-14-40(7-2,34(41)47)36(48)43(35,53)37(49)50/h8-12,14,19-20,25,34-36,44,48,52-53H,6-7,13,15-18,21-24H2,1-5H3,(H,49,50)

60223-75-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-O-Deacetylvinblastine-3-oic acid

1.2 Other means of identification

Product number -
Other names Vincaleukoblastin-23-oic acid,O4-deacetyl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:60223-75-8 SDS

60223-75-8Upstream product

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