602261-83-6

Basic information

• Product Name: 1-bromo-2-(isocyanomethyl)benzene
• Synonyms: 1-bromo-2-(isocyanomethyl)benzene
• CAS NO: 602261-83-6
• Molecular Weight: 196.046
• Mol File: 602261-83-6.mol

Chemical Properties

• CAS DataBase Reference: 1-bromo-2-(isocyanomethyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-bromo-2-(isocyanomethyl)benzene(602261-83-6)
• EPA Substance Registry System: 1-bromo-2-(isocyanomethyl)benzene(602261-83-6)

Safety Data

• Hazardous Substances Data: 602261-83-6(Hazardous Substances Data)

Upstream product

• 3433-80-5 1-Bromo-2-bromomethyl-benzene 
• 5465-63-4 2-bromobenzylamine hydrochloride 
• 6630-33-7 ortho-bromobenzaldehyde 

Downstream Products

• 1178564-12-9 C₂₆H₂₇BrClN₃O₃ 
• 1178564-10-7 C₂₂H₂₆BrN₃O₃ 
• 1178564-14-1 C₂₂H₂₈BrN₃O₄ 
• 1392000-68-8 N-(2-bromobenzyl)-3-oxo-2-(2-(pyridin-2-yl)ethyl)isoindoline-1-carboxamide 
• 1187828-78-9 C₁₂H₁₂BrNO 

Relevant articles and documents

Synthesis of 2,3-dihydro-1H-isoindole-1-thiones via the bromine-lithium exchange between 1-bromo-2-(1-isothiocyanatoalkyl)benzenes and butyllithium

The reaction of 1-bromo-2-(1-isothiocyanatoalkyl)benzenes, which are easily derived from 2-bromophenyl ketones or (2-bromophenyl)methanamine, with butyllithium generates 1-(1-isothiocyanatoalkyl)-2-lithiobenzenes, which immediately underwent intramolecula

Anodic Oxidation of Aminotetrazoles: A Mild and Safe Route to Isocyanides

A new electrochemical method for the preparation of isocyanides from easily accessible aminotetrazole derivatives has been developed, which tolerates an unprecedented range of functional groups. The use of chemical, rather than electrochemical, oxidation to afford isocyanides was also demonstrated, which provides access to these compounds for those without electrosynthesis equipment. The practicality of scale-up using flow electrochemistry has been demonstrated, in addition to the possibility of using electrochemically generated isocyanides in further reactions.

Isocyanide-based multicomponent reaction 'without' isocyanides

We present here a one-pot, four-component sequence that affords Ugi-type adducts starting from simple benzyl or allyl bromides. The isocyanides are prepared in situ under alkylation of silver cyanide salts and the resulting mixture is directly used in a U

One-pot synthesis of oxazoles using isocyanide surrogates

We wish to present herein a simple one-pot synthesis of 2,5-disubstituted oxazoles, starting from benzyl halides and acyl chlorides. The in situ formation of isocyanides, followed by the addition of an acyl chloride in the presence of a base leads to the