60246-67-5Relevant academic research and scientific papers
Organocatalytic Asymmetric Sulfa-Michael Addition of 2-Aminothiophenols to Chalcones: First Enantioselective Access to 2,3,4,5-Tetrahydro-1,5-benzothiazepines
Corti, Vasco,Camarero Gonzalez, Patricia,Febvay, Julie,Caruana, Lorenzo,Mazzanti, Andrea,Fochi, Mariafrancesca,Bernardi, Luca
supporting information, p. 49 - 52 (2017/01/14)
1,5-Benzothiazepine frameworks are highly relevant in medicinal chemistry. Reported catalytic asymmetric approaches to these scaffolds have targeted 2,3-dihydro-1,5-benzothiazepin-4-ones but leave the corresponding amines (i.e., 2,3,4,5-tetrahydro-1,5-ben
Novel and versatile methodology for synthesis of β-aryl-β- mercapto ketone derivatives as potential urease inhibitors
Ahari-Mostafavi, Mohammad Mahdi,Sharifi, Ali,Mirzaei, Mojtaba,Amanlou, Massoud
, p. 1113 - 1119 (2014/08/05)
The objective was to obtain new scaffold of compounds possessing anti-urease activity. For this new and simple method for the synthesis of β-aryl-β-mercapto ketone derivatives based on Michael addition of thiophenol to chalcones in an ionic liquid as a so
Animal bone meal (ABM): A novel natural catalyst for thia-michael addition
Riadi, Yassine,Mamouni, Rachid,Abrouki, Younes,Haddad, Mohammadine El,Saffaj, Nabil,Antri, Said El,Routier, Sylvain,Guillaumet, Gerald,Lazar, Said
experimental part, p. 269 - 271 (2011/07/08)
The preparation and use of Animal Bone Meal (ABM) as natural catalyst is described for C-S bond formation by thia-Michael addition. This new natural heterogeneous method led to β-sulfinyl adducts in very high yields after only a few minutes. Influence of
Fluoroboric acid adsorbed on silica-gel (HBF4-SiO2) as a new, highly efficient and reusable heterogeneous catalyst for thia-Michael addition to α,β-unsaturated carbonyl compounds
Sharma, Gaurav,Kumar, Raj,Chakraborti, Asit K.
, p. 4272 - 4275 (2008/09/21)
Fluoroboric acid adsorbed on silica-gel (HBF4-SiO2) has been found to be a new and highly efficient heterogeneous catalyst for thia-Michael addition to α,β-unsaturated carbonyl compounds under solvent-free conditions. In the case of
Scope and limitations of HClO4-SiO2 as an extremely efficient, inexpensive, and reusable catalyst for chemoselective carbon-sulfur bond formation
Khatik, Gopal L.,Sharma, Gaurav,Kumar, Raj,Chakraborti, Asit K.
, p. 1200 - 1210 (2007/10/03)
The scope and limitations of perchloric acid adsorbed on silica gel (HClO4-SiO2) as a highly efficient, inexpensive, and reusable catalyst for chemoselective carbon-sulfur bond formation by conjugate addition of thiols to α,β-unsatur
Natural phosphate modified with lithium nitrate: A new efficient catalyst for the construction of carbon-carbon, carbon-sulfur, and carbon-nitrogen bonds
Zahouily, Mohamed,Mounir, Bahija,Cherki, Hind,Bahlaouan, Bouchaib,Rayadh, Ahmed,Sebti, Said
, p. 1203 - 1217 (2008/02/02)
The addition of small amounts of lithium nitrate to natural phosphate followed by calcination gives a new catalyst Li/NP (weight ratio LiNO3/NP = 1/15). This material showed catalytic activity in the Michael addition of amines, mercaptans, and active methylene compounds to chalcone derivatives with high yields under mild reaction conditions. Li/NP is used as the catalyst for a facile synthesis of -amino acids, -sulfur acids, and 4 H-chromenes under heterogeneous conditions. The usual, undesirable byproducts from the Michael condensation such as 1,2-addition, bis-addition, and polymerization compounds are not observed with this method. The work-up procedure is simplified by simple filtration with the use of Li/NP.
Fluorapatite: Efficient catalyst for the Michael addition
Zahouily, Mohamed,Abrouki, Younes,Rayadh, Ahmed,Sebti, Sa?d,Dhimane, Hamid,David, Marc
, p. 2463 - 2465 (2007/10/03)
A Michael addition assisted by fluorapatite in heterogeneous media is described. Reaction between mercaptans and chalcone derivatives was studied at room temperature in methanol as solvent. By-products of usual undesirable reactions in Michael addition su
