60253-51-2Relevant academic research and scientific papers
A facile one-pot synthesis of some new spiro-thiazolidin-4-ones and benzimidazoles of biological interest
Metwally, Nadia Hanafy
, p. 34 - 43 (2008/12/21)
In a one-pot procedure, aromatic amines 1a-c, 9-fluorenone (2) and 2-mercaptoacetic acid (3) were converted into fluorenespiro-thiazolidinone derivatives 4a-c, which undergo condensation, oxidation and thiation to afford 6a-i, 7a-c, and 4-thioxo 8a-c, respectively. A new fluorenespiro-thiazolo- benzimidazole 10 was also obtained in one step via cyclocondensation of 1,2-phenylenediamine, 9-fluorenone and 2-mercaptoacetic acid. The obtained products seem to be interesting from the biological point of view.
