60298-18-2 Usage
Uses
Used in Pharmaceutical Industry:
5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID ETHYL ESTER is used as a key intermediate for the synthesis of various pharmaceuticals. Its role in the creation of complex molecules makes it instrumental in developing new drugs and improving existing ones.
Used in Agrochemical Industry:
In the agrochemical sector, 5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID ETHYL ESTER is utilized as a precursor in the production of various agrochemicals, contributing to the development of effective pesticides and other agricultural chemicals.
Used in Organic Synthesis:
5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID ETHYL ESTER is used as a building block in organic synthesis for creating more complex molecules. Its ability to form a variety of compounds makes it a valuable component in the synthesis of specialty chemicals.
Used in Fine Chemicals Production:
As a reagent, 5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID ETHYL ESTER is employed in the production of fine chemicals, where its properties are leveraged to produce high-quality and specialized chemical products for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 60298-18-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,2,9 and 8 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 60298-18:
(7*6)+(6*0)+(5*2)+(4*9)+(3*8)+(2*1)+(1*8)=122
122 % 10 = 2
So 60298-18-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H11NO3/c1-2-11-7(10)5-3-6(9)8-4-5/h5H,2-4H2,1H3,(H,8,9)
60298-18-2Relevant academic research and scientific papers
An improved procedure for the Beckmann rearrangement of cyclobutanones
Lachia, Mathilde,Richard, Fran?ois,Bigler, Raphael,Kolleth-Krieger, Amandine,Dieckmann, Michael,Lumbroso, Alexandre,Karadeniz, Ulfet,Catak, Saron,De Mesmaeker, Alain
supporting information, p. 1896 - 1901 (2018/04/19)
γ-Lactams are important building blocks for the synthesis of biologically active molecules and can easily be accessed via Beckmann rearrangement of cyclobutanones. However, Beckmann fragmentation is often a competing reaction for these strained ketones. We found that performing the Beckmann rearrangement with Tamura's reagent in the presence of aqueous HCl suppresses the undesired fragmentation reaction. This improved procedure was applied to a broad scope of substrates affording monocyclic, bicyclic, tricyclic or spirocyclic lactams. Our experimental results and DFT calculations suggest that the mechanism of the rearrangement probably involves a tetrahedral intermediate and doesn't proceed via oxime fragmentation as in a classical Beckmann rearrangement.
