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Azeliragon, also known as TV3326, is a small molecule drug specifically designed for the treatment of Alzheimer's disease. It functions by targeting and inhibiting the Receptor for Advanced Glycation End products (RAGE) in the brain, which is implicated in neuroinflammation and neurodegeneration associated with Alzheimer's. By blocking RAGE, azeliragon is intended to mitigate the buildup of amyloid-β plaques and the consequent inflammation and neuronal damage. Clinical trials have demonstrated promising results in enhancing cognitive and functional capabilities in early-stage Alzheimer's patients, with ongoing research to further elucidate and optimize its therapeutic potential.

603148-36-3

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603148-36-3 Usage

Uses

Used in Pharmaceutical Industry:
Azeliragon is used as a therapeutic agent for the treatment of Alzheimer's disease, aiming to improve cognitive and functional performance in patients by targeting the RAGE receptor and reducing associated neuroinflammation and neurodegeneration.
Used in Clinical Research:
Azeliragon is utilized as a subject of clinical trials to evaluate its efficacy and safety in early-stage Alzheimer's patients, with the goal of understanding its potential benefits and refining its therapeutic applications further.

Check Digit Verification of cas no

The CAS Registry Mumber 603148-36-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,0,3,1,4 and 8 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 603148-36:
(8*6)+(7*0)+(6*3)+(5*1)+(4*4)+(3*8)+(2*3)+(1*6)=123
123 % 10 = 3
So 603148-36-3 is a valid CAS Registry Number.
InChI:InChI=1/C32H38ClN3O2/c1-4-7-9-32-34-31(25-10-16-28(17-11-25)37-23-8-22-35(5-2)6-3)24-36(32)27-14-20-30(21-15-27)38-29-18-12-26(33)13-19-29/h10-21,24H,4-9,22-23H2,1-3H3

603148-36-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name Azeliragon

1.2 Other means of identification

Product number -
Other names TTP488

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:603148-36-3 SDS

603148-36-3Downstream Products

603148-36-3Relevant academic research and scientific papers

CRYSTALLINE FORMS OF [3-(4- -PHENOXY)-PROPYL]-DIETHYL-AMINE

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Page/Page column 6, (2008/12/04)

The present invention relates to crystalline forms of [3-(4-{2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1H-imidazol-4-yl}-phenoxy)-propyl]-diethylamine (“COMPOUND I”) useful in the treatment of RAGE mediated diseases.

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