603152-36-9Relevant academic research and scientific papers
CCR2: Characterization of the antagonist binding site from a combined receptor modeling/mutagenesis approach
Berkhout, Theo A.,Blaney, Frank E.,Bridges, Angela M.,Cooper, David G.,Forbes, Ian T.,Gribble, Andrew D.,Groot, Pieter H. E.,Hardy, Adam,Ife, Robert J.,Kaur, Rejbinder,Moores, Kitty E.,Shillito, Helen,Willetts, Jennifer,Witherington, Jason
, p. 4070 - 4086 (2003)
We describe here a classical molecular modeling exercise that was carried out to provide a basis for the design of novel antagonist ligands of the CCR2 receptor. Using a theoretical model of the CCR2 receptor, docking studies were carried out to define pl
