60319-09-7

Basic information

• Product Name: 3 5-DIMETHOXYPHENYL TRIFLUOROMETHANESUL&
• Synonyms: 3,5-DIMETHOXYPHENOL TRIFLUOROMETHANE, 9&;3,5-dimethoxyphenyl trifluoromethanesulfonate;3 5-DIMETHOXYPHENYL TRIFLUOROMETHANESUL&;3,5-DIMETHOXYPHENYL TRIFLATE
• CAS NO: 60319-09-7
• Molecular Formula: C₉H₉F₃O₅S
• Molecular Weight: 286.22
• Mol File: 60319-09-7.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 332.5°C at 760 mmHg
• Flash Point: >230 °F
• Appearance: /
• Density: 1.415 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.000281mmHg at 25°C
• Refractive Index: n20/D 1.4640(lit.)
• CAS DataBase Reference: 3 5-DIMETHOXYPHENYL TRIFLUOROMETHANESUL&(CAS DataBase Reference)
• NIST Chemistry Reference: 3 5-DIMETHOXYPHENYL TRIFLUOROMETHANESUL&(60319-09-7)
• EPA Substance Registry System: 3 5-DIMETHOXYPHENYL TRIFLUOROMETHANESUL&(60319-09-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/38
• Safety Statements: 26-36/37
• WGK Germany: 3
• Hazardous Substances Data: 60319-09-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H9F3O5S/c1-15-6-3-7(16-2)5-8(4-6)17-18(13,14)9(10,11)12/h3-5H,1-2H3

Upstream product

• 500-99-2 3,5-dimethoxyphenol 
• 421-83-0 trifluoromethane sulfonyl chloride 
• 358-23-6 trifluoromethylsulfonic anhydride 

Downstream Products

• 256510-14-2 O-tetrahydropyranyl-5-(3,5-dimethoxyphenyl)-4-pentyn-1-ol 
• 16147-07-2 1,3-dimethoxy-5-nitrobenzene 
• 628263-26-3 (3,5-dimethoxyphenyl)(phenyl)methanone 
• 1321821-99-1 (E)-3-benzylidene-5-(3,5-dimethoxyphenyl)furan-2(3H)-one 
• 1032400-18-2 2-(3,5-dimethoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane 
• 4179-19-5 1,3-dimethoxy-5-methylbenzene 
• 1132-21-4 3,5-dimethoxybenzoic acid 
• 500-66-3 Olivetol 
• 22976-40-5 1,3-dimethoxy-5-pentylbenzene 
• 7311-34-4 3,5-dimethoxybenzaldehdye 
• 146205-98-3 (E)-1,3-dimethoxy-5-(prop-1-en-1-yl)benzene 
• 64118-89-4 Methoxyeugenol 
• 22910-87-8 5-<(Z)-pentadec-8-enyl>resorcinol dimethyl ether 
• 61621-83-8 1,3-dimethoxy-5-<16'-(3'',5''-dimethoxyphenyl)-8'(Z)-hexadecen-1-yl>benzene 

Relevant articles and documents

Very long chain alkylresorcinols accumulate in the intracuticular wax of rye (Secale cereale L.) leaves near the tissue surface

Alkylresorcinols (ARs) are bioactive compounds occurring in many members of the Poaceae, likely at or near the surface of various organs. Here, we investigated AR localization within the cuticular wax layers of rye (Secale cereale) leaves. The total wax m

One-Pot Generation of Benzynes from Phenols: Formation of Primary Anilines by the Deoxyamination of Phenols

Benzynes were selectively generated in situ from phenols and trapped regioselectively with potassium hexamethyldisilazide to form primary anilines following acidic workup. The direct conversion of a phenolic hydroxyl group into a free amino group is a useful method for the preparation of primary aryl amines that are hard to synthesize by using coupling reactions involving phenol derivatives with ammonia. Whereas reactions of ortho- and meta-substituted phenols produced meta-substituted anilines exclusively, those of para-substituted phenols provided ortho-silylanilines.

Transition-Metal-Free C-C, C-O, and C-N Cross-Couplings Enabled by Light

Transition-metal-catalyzed cross-couplings to construct C-C, C-O, and C-N bonds have revolutionized chemical science. Despite great achievements, these metal catalysts also raise certain issues including their high cost, requirement of specialized ligands, sensitivity to air and moisture, and so-called "transition-metal-residue issue". Complementary strategy, which does not rely on the well-established oxidative addition, transmetalation, and reductive elimination mechanistic paradigm, would potentially eliminate all of these metal-related issues. Herein, we show that aryl triflates can be coupled with potassium aryl trifluoroborates, aliphatic alcohols, and nitriles without the assistance of metal catalysts empowered by photoenergy. Control experiments reveal that among all common aryl electrophiles only aryl triflates are competent in these couplings whereas aryl iodides and bromides cannot serve as the coupling partners. DFT calculation reveals that once converted to the aryl radical cation, aryl triflate would be more favorable to ipso substitution. Fluorescence spectroscopy and cyclic voltammetry investigations suggest that the interaction between excited acetone and aryl triflate is essential to these couplings. The results in this report are anticipated to provide new opportunities to perform cross-couplings.