60320-05-0

Basic information

• Product Name: (3a,5b,7a,12a)-3,12-dihydroxy-7-(sulfooxy)-Cholan-24-oic acid
• Synonyms: (3a,5b,7a,12a)-3,12-dihydroxy-7-(sulfooxy)-Cholan-24-oic acid;7-Sulfocholic acid;Cholic Acid 7-sulfate
• CAS NO: 60320-05-0
• Molecular Formula: C24H40O8S
• Molecular Weight: 488.63
• Mol File: 60320-05-0.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Density: 1.33g/cm³
• Refractive Index: 1.581
• CAS DataBase Reference: (3a,5b,7a,12a)-3,12-dihydroxy-7-(sulfooxy)-Cholan-24-oic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (3a,5b,7a,12a)-3,12-dihydroxy-7-(sulfooxy)-Cholan-24-oic acid(60320-05-0)
• EPA Substance Registry System: (3a,5b,7a,12a)-3,12-dihydroxy-7-(sulfooxy)-Cholan-24-oic acid(60320-05-0)

Safety Data

• Hazardous Substances Data: 60320-05-0(Hazardous Substances Data)

Usage

Description

(3a,5b,7a,12a)-3,12-dihydroxy-7-(sulfooxy)-Cholan-24-oic acid, also known as Cholic acid 7-sulfate, is a metabolite of the primary bile acid cholic acid. It is produced by the conjugation of a sulfate group with the hydroxy group at position 7 of cholic acid in the liver and gut. (3a,5b,7a,12a)-3,12-dihydroxy-7-(sulfooxy)-Cholan-24-oic acid plays a role in the digestion and absorption of dietary fats and fat-soluble vitamins.

Uses

Used in Pharmaceutical Industry:
(3a,5b,7a,12a)-3,12-dihydroxy-7-(sulfooxy)-Cholan-24-oic acid is used as a pharmaceutical compound for its role in the treatment of various liver and gallbladder disorders. It aids in the regulation of bile acid synthesis and metabolism, which can help alleviate symptoms and improve overall liver function.
Used in Research Applications:
In the field of scientific research, (3a,5b,7a,12a)-3,12-dihydroxy-7-(sulfooxy)-Cholan-24-oic acid is used as a research tool to study the effects of bile acids on lipid metabolism, cholesterol transport, and the enterohepatic circulation. This knowledge can contribute to the development of new therapies for related health conditions.
Used in Diagnostic Applications:
(3a,5b,7a,12a)-3,12-dihydroxy-7-(sulfooxy)-Cholan-24-oic acid can be utilized in diagnostic tests to evaluate the levels of bile acids in the body, which can provide insights into liver and gastrointestinal health. Abnormal levels may indicate the presence of certain diseases or disorders, guiding further medical evaluation and treatment.
Used in Nutritional Supplements:
As a component of bile acids, (3a,5b,7a,12a)-3,12-dihydroxy-7-(sulfooxy)-Cholan-24-oic acid may be included in nutritional supplements designed to support healthy digestion and absorption of fats and fat-soluble vitamins. This can be particularly beneficial for individuals with impaired bile acid production or those recovering from liver or gallbladder issues.

InChI:InChI=1/C24H40O8S/c1-13(4-7-21(27)28)16-5-6-17-22-18(12-20(26)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)32-33(29,30)31/h13-20,22,25-26H,4-12H2,1-3H3,(H,27,28)(H,29,30,31)/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-/m1/s1