60325-12-4

Upstream product

• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 462100-44-3 oxaziridine-2,3,3-tricarboxylic acid 2-tert-butyl ester 3,3-diethyl ester 
• 56572-27-1 tert-butyl N'-(1-phenylethylidene)hydrazinecarboxylate 
• 408346-61-2 2-(N-tert-butoxycarbonylimino)malonic acid diethyl ester 
• 68014-21-1 triphenyl(t-butoxycarbonylimino)phosphorane 
• 507-40-4 tert-butylhypochlorite 
• 16849-91-5 (R)-(+)-N-α-methylbenzylurea 

Downstream Products

• 29882-69-7 potassium anti-(R)-1-phenylethanediazoate 
• 143591-22-4 (-)-(R)-N-(1-phenylethyl)-N-nitrosohydrazine 
• 60362-49-4 (+)-(R)-(1-phenylethyl)hydrazine hydrochloride 
• 60325-13-5 (+)-(R)-1-Phenyl-aethylhydrazin 

Relevant academic research and scientific papers

Nickel-Catalyzed Asymmetric Hydrogenation of Hydrazones

An efficient nickel-catalyzed asymmetric hydrogenation of hydrazones to chiral hydrazines has been realized with up to 99 % yield and 99.4 : 0.6 er. Deuterium labelling experiments indicated that the hydrazone substrates undergo imine-enamine tautomerizat

Catalytic enantioselective hydrogenation of N-alkoxycarbonyl hydrazones: A practical synthesis of chiral hydrazines

(Figure presented) An enantioselective hydrogenation of hydrazones catalyzed by Rh complexes (Rh-Josiphos or Rh-Taniaphos) has been developed. The protocol can be applied to hydrazones with three different protective groups (Boc, Cbz, and methoxycarbonyl)

Oxaziridine-mediated amination of primary amines: Scope and application to a one-pot pyrazole synthesis

(Chemical Equation Presented) Electrophilic amination of primary aliphatic and aromatic amines is reported using a diethylketomalonate-derived oxaziridine to afford the corresponding N-Boc hydrazines in good to excellent yields. The method allows a one-pot synthesis of pyrazoles from primary amines.