6036-25-5 Usage
Uses
Used in Pharmaceutical Industry:
Narbomycin is used as an antibiotic for treating bacterial infections. Its macrolide structure allows it to target and disrupt bacterial protein synthesis, effectively inhibiting the growth and proliferation of various pathogenic bacteria.
Used in Research and Development:
In the field of medical research, narbomycin serves as a valuable compound for studying the mechanisms of antibiotic action and resistance. It can be utilized to develop new drugs or improve existing ones, potentially leading to more effective treatments for bacterial infections.
Used in Agricultural Industry:
Narbomycin can also be employed in the agricultural sector as a veterinary antibiotic to treat bacterial infections in livestock. This application helps maintain the health of animals and contributes to the overall productivity and sustainability of the industry.
Check Digit Verification of cas no
The CAS Registry Mumber 6036-25-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,0,3 and 6 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6036-25:
(6*6)+(5*0)+(4*3)+(3*6)+(2*2)+(1*5)=75
75 % 10 = 5
So 6036-25-5 is a valid CAS Registry Number.
InChI:InChI=1/C28H47NO7/c1-10-23-15(2)11-12-22(30)16(3)13-17(4)26(19(6)24(31)20(7)27(33)35-23)36-28-25(32)21(29(8)9)14-18(5)34-28/h11-12,15-21,23,25-26,28,32H,10,13-14H2,1-9H3/b12-11+/t15-,16-,17+,18?,19+,20-,21?,23-,25?,26+,28?/m1/s1
6036-25-5Relevant academic research and scientific papers
Total synthesis of pikromycin
Oh, Hong-Se,Kang, Han-Young
experimental part, p. 1125 - 1130 (2012/03/22)
The total synthesis of pikromycin (6), the first isolated macrolide antibiotic, was achieved. The target macrolide was retrosynthetically divided into two parts, pikronolide (6a) (aglycon) and d-desosamine. The aglycon was synthesized using key reactions
Macrolide biosynthesis: A single cytochrome P450, PicK, is responsible for the hydroxylations that generate methymycin, neomethymycin, and picromycin in Streptomyces venezuelae
Graziani, Edmund I.,Cane, David E.,Betlach, Melanie C.,Kealey, James T.,McDaniel, Robert
, p. 3117 - 3120 (2007/10/03)
The final step in the biosynthesis of methymycin, neomethymycin, and picromycin is an hydroxylation, shown to be carded out by the cytochrome P- 450 monooxygenase, PicK. Direct comparison of the relative k(cat)/K(m) values for the two substrates, YC-17 and narbomycin, showed a threefold rate preference of pick for narbomycin.
