60404-08-2 Usage
Uses
Used in Organic Synthesis:
(2E)-4-acetyl-5-hydroxy-2-(phenylmethylidene)furan-3(2H)-one is used as a key intermediate in organic synthesis for the preparation of various complex organic molecules. Its unique structure allows for versatile chemical reactions, making it a valuable building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (2E)-4-acetyl-5-hydroxy-2-(phenylmethylidene)furan-3(2H)-one is used as a lead compound for the development of new drugs. Its potential biological activities and pharmacological effects have been studied, and it may serve as a starting point for the design and optimization of novel therapeutic agents.
Used in Drug Development:
(2E)-4-acetyl-5-hydroxy-2-(phenylmethylidene)furan-3(2H)-one is used as a candidate molecule in drug development. Its unique structure and properties make it a promising candidate for further research and development into potential therapeutic agents, particularly in the areas of pharmaceuticals and agrochemicals.
Used in Materials Science:
In materials science, (2E)-4-acetyl-5-hydroxy-2-(phenylmethylidene)furan-3(2H)-one is used for the development of new materials with specific properties. Its unique chemical structure may contribute to the creation of advanced materials with applications in various industries, such as electronics, coatings, and adhesives.
Check Digit Verification of cas no
The CAS Registry Mumber 60404-08-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,4,0 and 4 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 60404-08:
(7*6)+(6*0)+(5*4)+(4*0)+(3*4)+(2*0)+(1*8)=82
82 % 10 = 2
So 60404-08-2 is a valid CAS Registry Number.
60404-08-2Relevant academic research and scientific papers
Dioxolanones as Synthetic Intermediates. Part 2. Synthesis of Tetronic Acids and Pulvinones
Ramage, Robert,Griffiths, Gareth J.,Shutt, Fiona E.,Sweeney, John N. A.
, p. 1539 - 1545 (2007/10/02)
The utility of 1,3-dioxolan-4-ones as intermediates in the synthesis of tetronic acids is examined.The reaction of dioxolanone (1) with lithium enolates of 2-substituted methyl or t-butyl acetates at -78 deg C in tetrahydrofuran afforded a general synthesis of 2-substituted tetronic acids (3) - (8).Treatment of (1) with the anions of 2-substituted acetonitriles led to formation of the corresponding 3-substituted-2-aminofuran-4(5H)-ones (13) and (14).A route to unsymmetrically substituted pulvinones by reaction of 5-arylidene-2,2-pentamethylene-1,3-dioxolan-4-ones with appropriately substituted phenylacetic ester anions has been devised.Thus, the preparation of the naturally occurring pigment 3',4',4-trihydroxypulvinone (18) was achieved via intermediate in which the phenolic groups were protected as benzyl ethers.The dioxolanone (26) has been used in the preparation of 2-acyl-4-benzylidenetetronic acids.
