60414-59-7

Usage

Uses

Used in Pharmaceutical Industry:
4-Phenyl-pyrimidine-2-thiol is used as a building block for the synthesis of various organic compounds, contributing to the development of new drugs. Its unique structure and properties make it a promising candidate for the creation of pharmaceutical agents with diverse therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Phenyl-pyrimidine-2-thiol is utilized as a precursor for the production of bioactive molecules. Its antimicrobial properties can be harnessed to develop agricultural products that protect crops from diseases and pests, thereby enhancing crop yield and quality.
Used in Antimicrobial Applications:
4-Phenyl-pyrimidine-2-thiol is employed as an antimicrobial agent due to its ability to inhibit the growth of various microorganisms. This property makes it a valuable component in the development of new drugs and agricultural products aimed at combating microbial infections and promoting overall health.
Used in Antioxidant Formulations:
Leveraging its antioxidant properties, 4-Phenyl-pyrimidine-2-thiol can be incorporated into formulations for various applications, such as in the development of health supplements, cosmetics, and food preservatives. Its ability to neutralize free radicals and protect against oxidative stress offers potential benefits in maintaining health and extending the shelf life of products.

InChI:InChI=1/C10H8N2S/c13-10-11-7-6-9(12-10)8-4-2-1-3-5-8/h1-7H,(H,11,12,13)

Upstream product

• 1131-80-2 (E)-3-(N,N-dimethylamino)-1-phenyl-2-propen-1-one 
• 17356-08-0 thiourea 

Downstream Products

• 56734-10-2 2-(methylsulfanyl)-4-phenylpyrimidine 
• 1361058-84-5 C₂₄H₂₂N₄S₂ 
• 1361058-85-6 C₂₅H₂₄N₄S₂ 
• 1361058-86-7 C₂₆H₂₆N₄S₂ 
• 1361058-81-2 C₂₁H₁₆N₄S₂ 
• 1361058-82-3 C₂₂H₁₈N₄S₂ 
• 1361058-83-4 C₂₃H₂₀N₄S₂ 

Relevant academic research and scientific papers

Reactions of α-acetylenic ketones with n-3-amidinothioureas. 1. Synthesis and properties of new derivatives of 1,3-thiazine

[4-Phenyl-2H-1,3-thiazin]-2-ylideneguanidinium perchlorate or acetoxytrifluoroborate respectively was obtained from the reaction of benzoylacetylene with N-amidinothiourea in glacial AcOH in the presence of an equimolar quantity of HClO4 or BF

Pyrimidine derivatives useful as nematicides

The invention provides novel compounds of formula (I) having nematicidal, insecticidal, acaricidal and fungicidal properties, compositions comprising them and processes and intermediates for their preparation: STR1 wherein R1 is --S(O)n CH2 CH2 CH=CF2 ; n is selected from 0, 1 and 2; R2, R3, and R4 are independently selected from hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, alkylcycloalkyl, optionally substituted aryl, optionally substituted arylalkyl, optionally substituted aryloxy, optionally substituted arylalkoxy, alkoxy, alkenyloxy, alkynyloxy, hydroxyalkyl, alkoxyalkyl, alkylthio, alkenylthio, alkynylthio, haloalkyl, haloalkenyl, haloalkynyl, haloalkoxy, haloalkenyloxy, haloalkynyloxy, haloalkylthio, haloalkenylthio, haloalkynylthio, halogen, hydroxy, cyano, nitro, --NR5 R6, --NR7 COR8, --NR9 SO2 R10, --N(SO2 --R11)(SO2 --R12), --COR13, --CONR14 R15, --COOR16, --OCOR17, --OSO2 R18, --SO2 NR19 R20, --SO2 R21, --SOR22, --CSNR23 R24, --SiR25 R26 R27, --OCH2 CO2 R28, --OCH2 CH2 CO2 R29, --CONR30 SO2 R31, --SO2 Z, or an adjacent pair of R2, R3 and R4 when taken together form a fused 5- or 6-membered carbocyclic or heterocyclic ring; R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, R19, R20, R21, R22, R23, R24, R25, R26, R27, R28, R29, R30 and R31 are independently selected from hydrogen, alkyl, alkenyl, alkynyl, haloalkyl, haloalkenyl, haloalkynyl, optionally substituted aryl and optionally substituted arylalkyl; and Z is halogen.

(Substituted-phenyl)-1,2,4-triazolo[4,3-a]-pyrimidines and (substituted-phenyl)-1,2,4-triazolo[1,5-a]pyrimidines

This disclosure describes substituted 1,2,4-triazolo[1,5-a]pyrimidines and substituted 1,2,4-triazolo[4,3-a]pyrimidines which possess anxiolytic activity.