6045-90-5

Upstream product

• 103724-99-8 2-bromo-5-chloro-1,3-dimethylbenzene 
• 68-12-2 N,N-dimethyl-formamide 
• 1634-04-4 tert-butyl methyl ether 

Downstream Products

• 90562-38-2 4-Chlor-2,6-dimethyl-benzaldoxim 
• 5757-62-0 anti-2,6-Dimethyl-4-chlor-N-methyl-benzaldoxim 
• 5757-60-8 syn-2,6-Dimethyl-4-chlor-benzaldehyd-O-methyloxim 
• 5757-57-3 syn-2,6-Dimethyl-4-chlor-banzaldoxim 
• 332179-32-5 4-chloro-2,6-dimethylbenzyl alcohol 
• 1315482-74-6 ethyl 2-(4-chloro-2,6-dimethylphenyl)acetate 
• 332179-33-6 (4-chloro-2,6-dimethylphenyl)acetonitrile 
• 186748-50-5 2-(4-chloro-2,6-dimethylphenyl)acetic acid 
• 31254-06-5 4-chloro-2,6-dimethyl-benzonitrile N-oxide 
• 5757-67-5 4-chloro-2,6-dimethylbenzonitrile 

Relevant academic research and scientific papers

COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION

The present disclosure relates generally to compounds and pharmaceutical compositions for the selective inhibition of histone lysine demethylase5 (KDM5), particularly KDM5B, and methods of their use in treating conditions and diseases associated with KDM5 activity.

PROCESS FOR PREPARING 2,6-DIALKYLPHENYLACETIC ACIDS

The invention relates to a multi-stage process for preparing 2,6-dialkylphenylacetic acids of the general formula (I) by reacting 2,6-dialkylbromobenzenes with (1) magnesium, (2) a formamide, (3) an acid, (4) hydrogenation of the benzaldehyde obtained, (5

Synthesis of arylacetates from benzylic alcohols and oxalate esters through decarboxylative coupling

Follow that dream: By combining a reversible transesterification between benzylic alcohols and dialkyl oxalates with catalytic decarboxylation of the resulting esters, a regiospecific C-C-bond-forming reaction to give α-arylacetates was achieved. In the overall process, CO2 and a volatile alcohol are the only byproducts. Various α-arylacetates were thus synthesized in high yields from easily accessible starting materials in the presence of catalytic amounts of Pd(OAc)2, dppp, and DABCO (see scheme). Copyright

Certain alkylene diamine-substituted pyrazlo (1,5-a)-1,5-pyrimidines and pyrazolo (1,5-a) 1,3,5-triazines

Disclosed are compounds of the formula: where R1, R2, R3, R4, R5, R6, and X are defined herein. These compounds are selective modulators of NPY1 receptors. These compounds are useful in the

Amino substituted pyrazolo[1,5,-a]-1,5-pyrimidines and pyrazolo[1,5-a]-1,3,5-triazines

Disclosed are compounds of the formula: where R1, R2, R3, R4, R5, R6, and X are defined herein. These compounds are selective modulators of NPY1 receptors. These compounds are useful in the