60472-24-4

Usage

General Description

1H-Imidazol-2-amine, 4-[1,1'-biphenyl]-4-yl- is a chemical compound with the molecular formula C18H15N3. It is a derivative of imidazole and biphenyl and is commonly used in pharmaceutical research and drug development. 1H-Imidazol-2-amine, 4-[1,1'-biphenyl]-4-yl- exhibits potential as an antifungal and antimicrobial agent, as well as a ligand for various biological receptors. Its structure and properties make it an important building block for the synthesis of novel chemical compounds for a wide range of applications. Studies have shown its potential for use in the treatment of various diseases and as a valuable tool in medicinal chemistry research.

Upstream product

• 56921-82-5 2-([1,1'-biphenyl]-4-yl)imidazo[1,2-a]pyrimidine 
• 135-73-9 2-Bromo-4'-phenylacetophenone 

Relevant academic research and scientific papers

Structure-activity relationship of 4(5)-aryl-2-amino-1 H -imidazoles, N 1-substituted 2-aminoimidazoles and imidazo[1,2- a ]pyrimidinium salts as inhibitors of biofilm formation by salmonella typhimurium and pseudomonas aeruginosa

A library of 112 4(5)-aryl-2-amino-1H-imidazoles, 4,5-diphenyl-2-amino-1H- imidazoles, and N1-substituted 4(5)-phenyl-2-aminoimidazoles was synthesized and tested for the antagonistic effect against biofilm formation by Salmonella Typhimurium and Pseudomo

Microwave-assisted synthesis of substituted 2-amino-1H-imidazoles from imidazo[1,2-a]pyrimidines

An efficient method for the synthesis of mono- and disubstituted 2-amino-1H-imidazoles via microwave-assisted hydrazinolysis of substituted imidazo[1,2-a]pyrimidines is reported. This protocol avoids strong acidic conditions and is superior to the classic