604785-27-5Relevant academic research and scientific papers
Design and synthesis of imidazoline derivatives active on glucose homeostasis in a rat model of type II diabetes. 1. Synthesis and biological activities of N-benzyl-N'-(arylalkyl)-2-(4',5'-dihydro-1'H-imidazol-2'- yl)piperazines
Rondu, Frédéric,Bihan, Gaelic Le,Wang, Xuan,Lamouri, Aazdine,Touboul, Estera,Dive, Georges,Bellahsene, Tounès,Pfeiffer, Bruno,Renard, Pierre,Guardiola-Lemaitre, Béatrice,Manechez, Dominique,Penicaud, Luc,Ktorza, Alain,Godfroid, Jean-Jacques
, p. 3793 - 3803 (1997)
The physiopathology of non-insulin-dependent diabetes mellitus is associated with a dysfunction in the regulation of insulin secretion. The α2-adrenoceptors have been reported to be involved in this alteration, although α2-antagonist
