60481-36-9

Basic information

• Product Name: 3,5-Dimethylphenylhydrazine hydrochloride
• Synonyms: LABOTEST-BB LT01148110;BIO-FARMA BF000371;3,5-DIMETHYLPHENYLHYDRAZINE;3,5-DIMETHYLPHENYLHYDRAZINE HCL;3,5-DIMETHYLPHENYLHYDRAZINE HYDROCHLORIDE;1-(3,5-DIMETHYLPHENYL)HYDRAZINE HYDROCHLORIDE;3,5-Dimethylphenylhydrazine hydrochloride 98%;3,5-Dimethylphenylhydrazine hydrochloride, tech.
• CAS NO: 60481-36-9
• Molecular Formula: C₈H₁₂N₂*ClH
• Molecular Weight: 172.66
• EINECS: 200-158-5
• Product Categories: Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes;Phenylhydrazine
• Mol File: 60481-36-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 180°C (dec.)
• Boiling Point: 247.3 °C at 760 mmHg
• Flash Point: 118.6 °C
• Appearance: White powder
• Vapor Pressure: 0.0259mmHg at 25°C
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Water Solubility: Soluble in water.
• CAS DataBase Reference: 3,5-Dimethylphenylhydrazine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Dimethylphenylhydrazine hydrochloride(60481-36-9)
• EPA Substance Registry System: 3,5-Dimethylphenylhydrazine hydrochloride(60481-36-9)

Safety Data

• Hazard Codes: Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39-45-24/25
• Hazardous Substances Data: 60481-36-9(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Uses

3,5-Dimethylphenylhydrazine hydrochloride participates inFischer indole synthesis protocol in biological evaluation of novel antitubercular indolecarboxamide derivatives against drug-susceptible and drug-resistant mycobacterium tuberculosis strains.

InChI:InChI=1/C8H12N2.ClH/c1-6-3-7(2)5-8(4-6)10-9;/h3-5,10H,9H2,1-2H3;1H

Upstream product

• 556-96-7 5-bromo-1,3-xylene 
• 108-69-0 3,5-dimethylaminoaniline 

Downstream Products

• 110570-17-7 3-{1-[(3,5-Dimethyl-phenyl)-hydrazono]-ethyl}-4-hydroxy-chromen-2-one 
• 112960-04-0 5-amino-1-(3,5-dimethylphenyl)-1H-pyrazole-4-carboxylic acid ethyl ester 
• 125240-55-3 methyl 2-(3,5-dimethylphenylhydrazono)-2-phenylacetate 

Relevant articles and documents

Synthesis of Aryl Hydrazines via CuI/BMPO Catalyzed Cross-Coupling of Aryl Halides with Hydrazine Hydrate in Water

The N,N’-bis(2,6-dimethylphenyl)oxalamide was discovered as a powerful ligand for Cu-catalyzed cross-coupling of aryl halides with hydrazine hydrate, leading to the formation of a variety of aryl hydrazines at 80 oC in water under the assistance of K3PO4 and 4 mol% cetyltrimethylammonium bromide from aryl bromides and aryl iodides. Good to excellent yields were observed in most cases.

Asymmetric catalysis on the nanoscale: The organocatalytic approach to helicenes

The first asymmetric organocatalytic synthesis of helicenes is reported. A novel SPINOL-derived phosphoric acid, bearing extended π-substituents, catalyzes the asymmetric synthesis of helicenes through an enantioselective Fischer indole reaction. A variety of azahelicenes and diazahelicenes could be obtained with good to excellent yields and enantioselectivities. Twisting indoles: A novel chiral Bronsted acid, specifically designed for long-range control on a nanoscale, catalyzes the asymmetric synthesis of azahelicenes through a Fischer indolization. The method has the advantage of starting from simple achiral starting materials, which can be modified by changing the protecting group (R2) or the terminal substituents (R1, R3). The products can be further oxidized to polyaromatic systems.

1-phenylpyrazole-4,5-dicarboxylic acid derivatives, composition containing them, and pollen formation inhibiting method of using them

Pollen formation in cereal grain plants is inhibited by application of a 4,5-dicarboxy or 5-carboxamido-4-carboxy (or derivatized carboxy)-1-(3,5-disubstitutedphenyl)pyrazole. Use of the compounds facilitates the production of hybrid seed.