6050-80-2Relevant academic research and scientific papers
Preparation method of light-driven molecular motor based on oxidized benzofuran structure
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, (2022/01/04)
The present invention relates to a preparation method and application of a molecular motor containing oxidized benzofuran structure, belonging to the field of organic chemistry technology. The first motor is based on 3-methyl-2,3-dihydrofyl-4(1H)-ketone and 2-coumarinone as raw materials, the second motor is based on 3-methyl-2,3-dihydrophenanthrene-4(1H)-keto and naphthalene [1,2-b]furan-2(3H)-ketone as raw materials, the third motor with 3-methyl-2,3-dihydrophenanthin-4 (1H)-keto and 6-isopropylphenone-2(3H)-keto as raw materials, in the presence of titanium tetrachloride and 1,8-diazoacyclodo-unicyclic-7-ene, In anhydrous tetrahydrofuran solvents, nucleophilic addition reactions are prepared. The reaction conditions of the present invention are mild, there is no need to add strong acids and strong bases, the equipment requirements are low, the operating cost is reduced; the reaction process produces less waste, the degree of environmental pollution is low; the obtained product motor structure is novel and has potential application value in the field of molecular devices.
Recent developments in the chemistry of heteroaromatic N -oxides
Wang, Youliang,Zhang, Liming
, (2015/02/19)
Selected developments in the chemistry of heteroaromatic N-oxides since 2001 are presented in this review. The use of these N-oxides, both in late-transition-metal-catalyzed oxidations of carbon-carbon triple bonds and in regioselective C-H functionalizations of the heteroarene, are contemporary topics of interest and the focus of the discussion. 1 Introduction 2 Synthesis of Heteroaromatic N-Oxides 2.1 Direct Oxidation of Hindered Heteroarenes 2.2 Through Construction of Heteroaromatic Rings 3 Heteroaromatic N-Oxides as Oxidants 3.1 Alkyne Oxidation 3.2 Allene Oxidation 3.3 Carbene Oxidation 4 Heteroaromatic N-Oxides as Substrates 4.1 Deoxygenative ortho-C-H Functionalization with Prior Activation 4.2 Deoxygenative ortho-C-H Functionalization with Nonstabilized Carbanions 4.3 Nondeoxygenative C-H Functionalization 4.3.1 ortho-C-H Functionalization 4.3.2 N-Oxide Directed ortho-Alkyl C-H Functionalization 4.3.3 N-Oxide Directed Remote C-H Functionalization 4.4 1,3-Dipolar Cycloaddition 5 Conclusion and Outlook.
Metal-free oxidative cyclization of alkynyl aryl ethers to benzofuranones
Graf, Katharina,Ruehl, Carmen L.,Rudolph, Matthias,Rominger, Frank,Hashmi, A. Stephen K.
, p. 12727 - 12731 (2013/12/04)
Readily available phenols can be converted into substituted aryl alkynyl ethers, which react with an N-oxide as an oxidant and catalytic amounts of a Bronsted acid to provide benzofuranones. If non-terminal alkynyl ethers are applied, a 1,2-hydride shift takes place and phenyl acrylates are obtained. Thus activated alkynes can serve as α-oxy carbene precursors even in the absence of a metal catalyst. Copyright
Anionic Homologous Fries Rearrangement of O-(2-Methylaryl)carbamates. A Regiospecific Route to Benzo[b]furan-2(3H)-ones including an Unnamed Metabolite from Helenium Species
Kalinin,Miah,Chattopadhyay,Tsukazaki,Wicki,Nguen,Coelho,Kerr,Snieckus
, p. 839 - 841 (2007/10/03)
A new LDA mediated O → C carbamoyl migration, 3 provides a general and efficient route to aryl acetamides 5, precursors to the benzo- and naphthofuranones 7, one of which serves as a starting material for a short synthesis of naturally-occurring benzofuranolactol 11 isolated from several Helenium species.
