6051-17-8Relevant academic research and scientific papers
An easy approach to butenolides by Horner-Wadsworth-Emmons olefination of α-hydroxy ketones
Bonadies, Francesco
, p. 2839 - 2840 (1995)
By treatment with stabilized lithium phosphonates in the presence of activated 4A molecular sieves, unprotected α-hydroxy ketones 1 undergo a convenient Horner-Wadsworth-Emmons olefination to give directly butenolides 3 as exclusive or predominant products.
A Synthesis of Fused Butenolides.
Larson, Gerald L.,Prieto, J. Antonio,Gonzalez, Patricia
, p. 2779 - 2782 (2007/10/02)
It has been shown that tert-butyldimethylsilylated (Z) 2-carboethoxymethylene cycloalkanols are readily desilylated with concomitant cyclization to give the corresponding butenolides.The (E) isomers are desilylated, but not cyclized under these conditions.
