6051-75-8

Upstream product

• 78158-91-5 N,N-dimethyl-N'-(4H-1,2,4-triazol-3-yl) formamidine 

Downstream Products

• 223647-73-2 5-oxo-7-phenyl-4,5,6,7-tetrahydro-1,2,4-triazolo[1,5-a]pyrimidine 
• 1378233-00-1 10-benzylidene-6-phenyl-6,7,8,9,10,11-hexahydrobenzo[g][1,2,4]triazolo[3,4-a]quinazolin-5-ol 
• 1378232-97-3 10-benzylidene-6-phenyl-6,7,8,9,10,11-hexahydrobenzo[g][1,2,4]triazolo[4,3-b]quinazolin-5-ol 
• 1378232-96-2 9-benzylidene-6-phenyl-7,8,9,10-tetrahydro-6H-cyclopenta[g][1,2,4]triazolo[3,4-b]quinazolin-5-ol 
• 1378232-99-5 9-benzylidene-6-phenyl-7,8,9,10-tetrahydro-6H-cyclopenta[g][1,2,4]triazolo[3,4-a]quinazolin-5-ol 
• 40775-90-4 5-chloromethyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one 

Relevant academic research and scientific papers

Kinetics and mechanism of uncatalyzed and ruthenium(III)-catalyzed oxidation of formamidine derivative by hexacyanoferrate(III) in aqueous alkaline medium

The catalytic effect of ruthenium(III) on the oxidation of N, N-dimethyl- N′-(4H-1,2,4-triazol- 3-yl) formamidine (ATF) by hexacyanoferrate(III) (HCF) was studied spectrophotometrically in aqueous alkaline medium. Both uncatalyzed and catalyzed reactions showed first order kinetics with respect to [HCF], whereas the reaction orders with respect to [ATF] and [OH ?] were apparently less than unity over the concentration range studied. A first order dependence with respect to [RuIII] was obtained. Increasing ionic strength increased the rate of uncatalyzed reaction and decreased the rate of the catalyzed one Plausible mechanistic schemes of oxidation reactions have been proposed. In both cases, the final oxidation products are identified as aminotriazole, dimethyl amine and carbon dioxide. The rate laws associated with the reaction mechanisms are derived. The reaction constants involved in the different steps of the mechanisms were calculated. The activation and thermodynamic parameters have been computed and discussed. [Figure not available: see fulltext.]

Kinetic and Mechanistic Aspects of Oxidation of Aminotriazole Formamidine by Cerium(IV) in Aqueous Perchloric and Sulfuric Acid Solutions: A Comparative Study

The kinetics of the oxidation of an aminotriazole formamidine derivative, N,N-dimethyl-N′-(4H-1,2,4-triazol-3-yl) formamidine (ATF) by cerium(IV) has been studied spectrophotometrically in aqueous perchloric and sulfuric acid solutions at constant ionic strength of 1.0 mol·dm-3. In both acids, the reaction shows first order kinetics with respect to [Ce(IV)], whereas the orders with respect to [ATF] are less than unity. The reaction exhibits negative fractional order kinetics with respect to [H+]. The rates of reaction are not significantly affected by variations of either ionic strength or relative permittivity of the reaction's media. Addition of cerium(III) product does not affect the rates. Plausible mechanistic schemes for the reactions have been proposed. In both cases, the final oxidation products were identified as aminotriazole, dimethyl amine and carbon dioxide. Under comparable experimental conditions, the oxidation rate in perchloric acid solution is about sixfold higher than that in sulfuric acid solution. The effect of temperature on the rates has also been studied and activation parameters have been evaluated and discussed. The rate laws associated with the reaction mechanisms are derived.