60524-14-3 Usage
Uses
Used in Pharmaceutical Industry:
Nicotinamide is used as a dietary supplement for its essential role in energy production and maintaining overall health. It is particularly beneficial for individuals with vitamin B deficiency, as it helps in the prevention and treatment of various health issues related to the deficiency.
Used in Skincare Industry:
Nicotinamide is used as an active ingredient in skincare products for its anti-inflammatory and antioxidant properties. It helps in managing certain skin conditions, such as acne, by reducing inflammation and promoting a healthy skin barrier. Additionally, it aids in improving skin texture and reducing the appearance of fine lines and wrinkles.
Used in Anti-Aging Applications:
Nicotinamide is used as an anti-aging agent due to its role in DNA repair and its ability to stimulate the production of collagen, a protein responsible for maintaining skin elasticity. By promoting collagen synthesis, it helps in reducing the signs of aging and maintaining youthful skin.
Used in Neurological Applications:
Nicotinamide is used in the management of neurological conditions, such as Alzheimer's disease and Parkinson's disease, due to its role in energy production and its potential to protect neurons from oxidative stress. It has been found to improve cognitive function and delay the progression of neurodegenerative diseases.
Used in Research and Development:
Nicotinamide is used in scientific research for its involvement in various metabolic processes, including DNA repair, aging, and inflammation. It serves as a valuable tool in understanding the underlying mechanisms of these processes and developing potential therapeutic interventions for related health conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 60524-14-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,5,2 and 4 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 60524-14:
(7*6)+(6*0)+(5*5)+(4*2)+(3*4)+(2*1)+(1*4)=93
93 % 10 = 3
So 60524-14-3 is a valid CAS Registry Number.
InChI:InChI=1/C6H7N3O/c7-5-1-4(6(8)10)2-9-3-5/h1-3H,7H2,(H2,8,10)
60524-14-3Relevant academic research and scientific papers
PIPERIDIN-1- YL-N-PYRYDI NE-3-YL-2-OXOACET AM IDE DERIVATIVES USEFUL FOR THE TREATMENT OF MTAP-DEFICIENT AND/OR MT A-ACCUMULATING CANCERS
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Paragraph 0544, (2022/02/09)
Compounds are provided according to Formula (I) and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof; wherein R1, R2, R3, R4, R6, R7, R8 and n are as defined herein. Compounds of the present invention are contemplated useful for the prevention and treatment of a variety of conditions.
BENZAMIDE FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS
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Page/Page column 75-76, (2010/09/17)
The present invention provides novel benzamide derivatives of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein the variables A, W, Y, Z, R8, and R9 are as defined herein. These compounds are selective inhibitors of factor VIIa which can be used as medicaments.
Synthesis of (aryloxyacetylamino)-isonicotinic/nicotinic acid analogues as potent hypoxia-inducible factor (HIF)-1α inhibitors
Boovanahalli, Shanthaveerappa K.,Jin, Xuejun,Jin, Yinglan,Kim, Jin Hwan,Dat, Nguyen Tien,Hong, Young-Soo,Lee, Jeong Hyung,Jung, Sang-Hun,Lee, Kyeong,Lee, Jung Joon
, p. 6305 - 6310 (2008/09/17)
We report a new series of HIF-1α inhibitors which were obtained through structural modifications of previously reported lead 1. The in vitro inhibitory potencies of newly synthesized compounds were evaluated against hypoxia-induced HIF-1 activation using
